Urine protein +- indicates that the urine protein excretion is slightly higher than the normal level of 150mg/24h, showing a weak positive phenomenon, generally does not indicate the existence of serious diseases, patients do not need to worry too much, weak positive urine protein is common in the following phenomena: 1, physiological causes: long-term upright activity, overwork, strenuous exercise, severe cold, emotional excitement, and female menstruation and other factors will induce renal vascular Spasm congestion, increased permeability of the glomerular filtration membrane, which will lead to increased urinary protein excretion, such patients generally do not need special intervention, with the lifting of the trigger, urinary protein will return to normal. In addition, excessive intake of high-protein diet and mixing vaginal secretions or semen in the sample can also lead to weakly positive urine protein; 2, pathological reasons: Patients with weakly positive urine protein can go to the hospital later for re-examination, and the results still show weakly positive, probably due to pathological reasons resulting in increased permeability of the glomerular basement membrane, resulting in protein loss, which should be combined with other indicators in the urine and kidney function tests, CT It is necessary to combine the results of other indicators in the urine and renal function tests, CT and other tests to determine the cause. It is commonly seen in various kidney diseases such as glomerulonephritis, pregnancy nephropathy, hypertensive nephropathy, early diabetic nephropathy, etc. Since the urine protein result is only slightly weakly positive, it is usually not serious and has a good prognosis as long as it is actively treated.