Foot fungus is often caused by vitamin B1 deficiency, so how does vitamin B1 deficiency lead to foot fungal heart disease?
Mechanism.
1, VitB1 is an important coenzyme of sugar metabolism, its deficiency can make the concentration of pyruvate and lactate in the blood increase, the peripheral small arteries dilate, the peripheral vascular resistance decreases, then the amount of venous blood return to the heart will increase, leading to an increase in cardiac load.
2.Due to VitB1 deficiency, it leads to heart metabolism disorder and lactic acid accumulation, resulting in interstitial edema and fibroplasia of myocardium and enlargement of both sides of the heart, leading to high output type heart failure.
3, VitB1 in the body basically can not be synthesized, relying on exogenous supply, and the amount required is affected by the composition of the diet, fat protein as the main component of the diet, VitB1 needs to be reduced; when eating more sugar, the amount required also increased. On the basis of long-term VitB1 deficiency, if the labor intensity is high, and the diet is high in calories and mainly sugar, it is easy to induce pediculosis heart disease.
Clinical manifestations.
It manifests as enlarged heart, dilated peripheral blood vessels, tachycardia at rest, shortness of breath, chest pain, and edema. If not treated in time, it can lead to acute heart failure, which often occurs suddenly and critically, with extreme respiratory distress, accelerated heart rate, marked enlargement of the cardiac turbinate to the second side, a pendulum sound, a systolic murmur in the precordial region, and a hyperactive second heart sound in the pulmonary artery.
Arterial pressure is slightly low, pulse pressure difference is large, venous pressure is significantly elevated, and carotid and femoral artery pulsations are enhanced. The liver was enlarged, and there was generalized swelling and oliguria. The electrocardiogram shows tachycardia, shortened P-R interval, biphasic or inverted T waves, low voltage, and prolonged Q-T interval. In infants and young children, cardiac involvement is predominant, manifesting as loss of appetite, vomiting, restlessness, insomnia, and rapid progression may lead to corkscrews, convulsions, heart failure, and death. The mother of the child is often a patient with occult or clinically manifested pediculosis.
Diagnosis.
It is mainly based on the history of nutritional deficiency and clinical manifestations. The diagnosis of peripheral neuritis can be determined by the following methods.
① squatting test, the patient takes a squatting position, that is, the calf pain, difficulty in standing up, often used to support the knee to help stand up;
② pain when squeezing the gastrocnemius muscle;
③The dorsum of the foot, ankle and lower calf are hyperalgesic and hyperalgesic;
④Ankle and knee reflexes are abnormal, mostly diminished or absent.
The diagnosis of fulminant pediculosis heart disease is based on
① history of vitamin B1 nutritional deficiency for more than 3 months and signs of peripheral neuritis;
(ii) sudden onset of high output heart failure with irritable thirst;
③ Heart enlargement, regular rhythm, no other etiology to be found;
④For suspected cases, immediate therapeutic tests are performed, and the symptoms of this disease improve rapidly after treatment.
Treatment.
General vitamin B1 deficiency can be used oral thiamine tablets 5-10mg, 3 times a day. If it cannot be taken orally or if it is poorly absorbed in the intestine, 10mg can be injected intramuscularly once or twice a day. In critical cases, 50-100mg of thiamine should be given intravenously or intramuscularly immediately. Later, 20-40mg should be injected every 4 hours, and heart failure edema can be supplemented with diuretics until the symptoms of heart failure disappear.
Generally the symptoms can be relieved within 24-96 hours, then change to oral thiamine 10mg 3 times a day. Yeast tablets or compounded vitamin B are also given to prevent or supplement other B vitamin deficiencies in the body. Diseases that trigger the disease, such as typhoid fever, gastrointestinal diseases, hyperthyroidism, diabetes mellitus, etc., should also be treated actively.
Prevention.
At present, in remote mountainous areas and relatively backward economic conditions, foot disease is still prevalent and should be given attention. In daily life, attention should be paid to the method of rice panning and cooking to avoid the loss of VitB1, pay attention to the supplementation of VitB1, and foot fungal heart disease can be prevented.