Kidney disease can cause hypertension. Chronic kidney disease, especially in patients with deteriorating renal function to stage IV-V, is often combined with hypertension for the following reasons: i. Water and sodium retention. Chronic kidney disease patients with decreased glomerular filtration rate can lead to water and sodium retention, causing edema and cardiac insufficiency in patients, leading to hypertension or hypertension that is difficult to control. Second, sympathetic hyperfunction, chronic kidney disease patients due to uremic toxin accumulation, insomnia and many other reasons, so that sympathetic hyperfunction, causing vasoconstriction leading to the occurrence of hypertension. Third, acidosis, chronic kidney disease patients due to decreased glomerular filtration rate, renal tubular acid secretion dysfunction, metabolic acidosis will occur, causing peripheral vasoconstriction, leading to the occurrence of hypertension.