Drugs for hypertension include short-acting drugs as well as long-acting drugs. Common short-acting drugs include nifedipine tablets, which can cause myocardial ischemia because they can cause an increase in heart rate and increase the oxygen consumption of the heart muscle. Myocardial ischemia is a pathological state in which the blood perfusion to the heart is reduced, resulting in decreased oxygen supply to the heart and abnormal myocardial energy metabolism that does not support the normal work of the heart. The energy required for cardiac activity is provided almost exclusively by aerobic metabolism, so that the rate of blood oxygen uptake by the myocardium is high even when it is quiet. Under normal circumstances, the body can promote a relatively constant blood supply and demand through its own regulation to ensure the normal work of the heart, but when some cause causes an imbalance in myocardial blood supply and demand, it leads to myocardial ischemia in the true sense. Nifedipine tablets, because they can cause an increased heart rate, increased myocardial oxygen consumption, and the occurrence of myocardial ischemia, are, for the time being, largely eliminated, except when applied in conditions requiring emergency treatment for hypertensive emergencies.