Clinical manifestations of malignant lung tumor are divided into symptoms and signs caused by primary tumor, local expansion or distant metastasis of tumor, and extrapulmonary manifestations. 1. Symptoms and signs caused by primary tumor: including cough, blood in sputum or hemoptysis, shortness of breath or wheezing, chest pain, fever and emaciation. 2. Symptoms and signs caused by local progression of the tumor, such as chest pain or pleural effusion caused by tumor invasion of pleura or chest wall, hoarseness caused by direct or metastatic lymph node compression of the recurrent laryngeal nerve, dysphagia caused by invasion or compression of esophagus, pericardial effusion caused by invasion of the pericardium, and ptosis of the affected side of the eyelid, pupil shrinkage, inward depression of the eyeballs, and absence of sweating of the frontal area or chest wall of the same side due to compression of the sympathetic nerves. 3. Symptoms and signs caused by distant metastasis of the tumor: metastasis of the tumor to the central nervous system can cause headache, vomiting, etc.; metastasis to the bones can cause pathological fracture; metastasis to the abdomen can cause abdominal distension, liver enlargement, jaundice, loss of appetite, etc.; metastasis to lymph nodes can be seen as lymph node enlargement, and supraclavicular lymph nodes are more common. 4. Extrapulmonary manifestations: also known as paraneoplastic syndrome, which is more common in small-cell lung cancer, and can be manifested as Cushing’s syndrome, hypercalcemia, and abnormalities of bone or blood system.