The fastest treatment for hives is not erythromycin ointment. Erythromycin ointment belongs to the antibiotic, mainly used for the treatment of local bacterial infections, purulent dermatosis, small burns, ulcer surface infections and common acne, etc.; hives using erythromycin only has an anti-inflammatory and bactericidal, to slow down the role of itching. Urticaria belongs to a kind of allergic disease, the pathogenesis is mainly related to contact with allergic substances, infections, immune response and other factors, the treatment of urticaria can be through the oral antihistamine drugs, such as H1 receptor antagonists have paracetamol, loratadine. If the symptoms of urticaria are more serious, intravenous infusion of calcium gluconate, vitamin C or glucocorticoids such as dexamethasone can also be considered for treatment. Patients should pay attention to avoid spicy stimulating food, light diet, eat more vegetables and fruits, ensure sufficient rest, avoid contact with allergens. If patients need to treat hives or use erythromycin ointment, please standardize the use of medication under the guidance of a professional doctor, do not blindly self-medication.