In the Department of Otolaryngology, a considerable number of pediatric patients require surgical treatment, which requires general anesthesia, and many parents have ideological concerns about their children undergoing general anesthesia surgery, worrying about the impact on the body and memory, so does general anesthesia have an impact on the body? The so-called general anesthesia refers to the respiratory inhalation of anesthetics or intravenous injection of anesthetics, the inhibition of the central nervous system, the loss of general pain, reflex inhibition and skeletal muscle relaxation, the body is unconscious, the doctor in the patient painless, restful sleep in the case of various surgeries. The commonly used drug for inhalation of the respiratory tract during anesthesia is desflurane, which has low tissue solubility, rapid induction of anesthesia, early awakening, almost no metabolites in the body, and little effect on the body’s function. Recovery after anesthesia with desflurane is faster than other halogenated volatile anesthetics. The blood-gas partition coefficients of various anesthetics are as follows: 0.42 for desflurane, 0.47 for nitrous oxide (laughing gas), 1.48 for isoflurane, and 2.3 for halothane; after anesthesia with 0.65 alveolar minimum effective concentration of desflurane and isoflurane with 60% nitrous oxide/oxygen respectively, the recovery period was 5.8 points for desflurane and 7.9 points for isoflurane, based on the time of the first movement other than coughing. The time to elicit speech signal response was 7.8 for desflurane and 14.0 for isoflurane, which is significantly lower than isoflurane, indicating that it is effective and safe. The commonly used intravenous general anesthetic is isoproterenol, which is a milky white liquid that doctors often call “milk”. Isoproterenol is highly lipophilic and has the characteristics of rapid distribution from the blood to the central nervous system and peripheral tissues, so it has a rapid onset of action, and is generally administered by micro-pump, with a controlled and stable depth of anesthesia, and its clearance is mainly in the liver, with a clearance half-life of 30-60 minutes, rapid metabolism, no significant accumulation, and quick and complete awakening. During the process of general anesthesia, the patient’s oxygen concentration, blood pressure and heartbeat are within the normal range, and the nerve cells in the brain are not damaged. The anesthesiologist only suppresses the central nervous system by regulating the drug concentration, and this suppression is completely reversible. It is like waking up from a nap. In addition, the common diseases that need surgical treatment for children in ENT are chronic tonsillitis, adenoid hypertrophy and secretory otitis media. Doctors recommend whether the child needs surgical treatment according to the severity of the disease and the effect of medication, because surgery can solve the pain and the source of the disease in the child, otherwise, snoring, breath-holding and hearing loss caused by these diseases may affect the growth and development of the child, life communication and listening and learning, and a blanket refusal of surgery will only expose the child to greater adverse effects. Therefore, general anesthesia is only a basic guarantee for completing the surgery, which itself will not damage the child’s body. What parents need to consider is to recognize the child’s disease, understand the treatment plan and the necessity of the surgery with the doctor’s explanation, and give their baby a healthy body and a happy childhood together with the doctor.