Patients often consult which drugs cannot be taken for epilepsy. If you take other drugs, it is recommended to remind your doctor that you have a history of epilepsy and read the drug instructions carefully, and avoid taking drugs that are marked for caution or prohibited for epilepsy. The quinolones: including pyridoxine, haloperidol (norfloxacin), fludioxonate (enoxacin), ciprofloxacin (ciprofloxacin), etc.. Among them, ciprofloxacin causes the incidence of central nervous system toxic side effects of 0.4% to 2.2%. Cleary et al. reported that treatment with ciprofloxacin caused sudden and severe convulsions. It is thought to be due to the drug blocking the binding of antiepileptic drugs to receptors in the brain, leading directly to neurotoxicity. Recent studies have demonstrated that quinolones inhibit the binding of the inhibitory transmitter γ-aminobutyric acid (GABA) to receptor sites in the brain, which increases excitability of the central nervous system, leading to spasms and induced isoniazid, one of the most common antituberculosis drugs, is highly selective for Mycobacterium tuberculosis and has strong bactericidal effects. Isoniazid is used with caution in epileptic patients. If the dose is too high or the duration of administration is too long, it can cause adverse neurological reactions, manifested as numbness, burning pain, tingling, insomnia, myalgias, and induced convulsions in the limbs. The mechanism is related to isoniazid and vitamin B6 similar and compete for the same enzyme system or both combined into hydrazone excreted by urine, resulting in vitamin B6 deficiency, which can be prevented by vitamin B6. Tricyclic antidepressants: including promethazine, amitriptyline, meptyline, Ritalin, etc.. These drugs have a certain excitatory effect and can cause convulsions or induce seizures when applied in high doses or for longer periods of time. Promethazine is prohibited in patients with epilepsy, and other antidepressants should be used with caution. Anticholinesterase drugs: neostigmine bromide, neostigmine methosulfate, galantamine hydrobromide, are reversible anticholinesterase drugs, mainly through the inhibition of cholinesterase, acetylcholine accumulation and present M-like and N-like effects. It can cause muscle tremors and induce seizures, so it should be prohibited. Anthelmintic intestinal wormer: (albendazole) is a highly effective, broad-spectrum, low-toxicity intestinal anthelmintic, effective against nematodes, trematodes and tapeworms, and should be contraindicated because it is likely to induce seizures. Anti-cold medicine containing paracetamol: such as: ketamine, cold and flu, cold and flu spirit, quick-acting cold and flu capsules, Lixu, (new) Contec, etc. Cough medicines containing opioids, codeine or paracetamol: e.g.: compound licorice tablets, strong cough syrup, federal cough syrup, Chili cough syrup, rock white cabbage, etc. Do not inject penicillin intravenously: avoid metronidazole, tinidazole, etc. Various diet pills; female epilepsy patients who love beauty should pay attention to the fact that they can exercise properly to lose weight, do not take diet pills to lose weight, and female epilepsy patients who have fertility requirements should not take sodium valproate. Chinese medicine of ephedra, poppy husk, epiphyllum, etc.