Cold urticaria is mostly considered as cold urticaria, which can be divided into two types, one is familial, which is autosomal dominant and relatively rare, starting from infancy and lasting for life. The other type is acquired, which is characterized by pruritic wind and itchy wind masses in the cold area after contact with cold wind, cold water or other cold substances, and in severe cases, angioedema, hand numbness, chest tightness, abdominal pain, diarrhea and other symptoms, and even shock. In addition, cold urticaria may also be one of the clinical manifestations of certain diseases, such as cryoglobulinemia and paroxysmal cold hemoglobinuria. When cold urticaria occurs, it is recommended to seek medical attention at a hospital dermatology department promptly and choose treatment medications according to your personal condition and doctor’s recommendations. In addition to the commonly used antihistamines, ketotifen, cyproheptadine, doxepin and other drugs can be used for treatment. In addition, cold desensitization treatment can be performed by repeated exposure to cold water baths under the guidance of a doctor. Patients with severe cases of shock should be taken to a doctor immediately. Patients who get hives when it is cold should try to avoid prolonged exposure to cold environments, avoid contact with cold water or other cold objects, and increase clothing appropriately when it is cold. If the skin itching is severe, you should follow medical advice and not scratch the skin frequently to avoid skin infection.