An elderly woman from Anhui province had a stage I bilateral knee surface replacement surgery in a local hospital. After the surgery, the right knee joint had repeated redness and pain, sinus tract formation, and pus flow for 2 years, and the knee joint was almost straight and could only be flexed 20 degrees. The front of the knee joint had a lot of scars due to repeated incision and drainage, sinus tract formation, etc. The x-ray at the time of the visit to our hospital showed that the knee joint still had obvious inversion, the prosthesis was loose, and the surrounding bone reacted significantly, through a comprehensive assessment, we decided to adopt a two-stage revision surgery plan The original prosthesis was removed in the first stage, a thorough debridement was performed, a movable antibiotic-containing bone cement spacer was installed, and postoperative antibiotic therapy was intensified to first After three months, the patient’s inflammatory indexes returned to normal, and he returned to our hospital for the second revision. After the second revision surgery, the patient’s lower limb force lines returned to normal, and the joint mobility improved significantly, better than the left knee.