Urticaria patients may get better after taking loratadine once, usually a single dose will not completely cure. Urticaria is generally due to allergies, infections, immunity and other factors caused by systemic or local reactions, the skin may appear in varying sizes, with intense itching. Loratadine, an antihistamine, is an effective treatment for antagonizing histamine-induced allergic reactions. In a very small percentage of patients, hives may resolve completely after a single dose of loratadine; however, the vast majority of patients usually do not get better or completely cured after a single dose because the therapeutic concentration of the drug has not yet been reached. Because the allergic reaction will continue for a period of time, antihistamines also need a period of time to play the role of anti-allergy, so one time after the use of the drug can not completely control the symptoms. To completely treat urticaria, first of all, we should find and completely away from the causes, such as allergens, infectious factors, etc., and at the same time, follow the doctor’s instructions for regular oral antihistamines, usually after a period of oral medication, urticaria can be effectively controlled. Urticaria patients are advised to go to the hospital in time and follow the doctor’s instructions for standardized treatment. Do not eat spicy stimulating food during the treatment, and do not eat fish and shrimp and other easily allergic seafood ingredients.