I. Symptoms 1. Endocrine symptoms: (1) Prolactin-secreting type: Women manifest amenorrhea, lactation, and infertility. In men, the symptoms are low sexual function, such as decreased libido, impotence and infertility. (2) Growth hormone-secreting type: The main manifestations are gigantism (common in adolescents), facial changes, coarse hands and feet, excessive sweating, bone and joint lesions, carpal tunnel syndrome, and swelling of the soft tissues and joints of the fingers (toes) of the hands and feet. Severe diabetes mellitus, hypertrophic heart disease, and tumors of the thyroid and colon, etc. (3) Adrenocorticotropic hormone (ACTH) secretion type: Mainly manifested as centripetal obesity, full-moon face, acne, hirsutism, purple lines (purple-red skin lines on the body). Increased blood pressure, low blood potassium and diabetes mellitus. Often combined with mental illness. (4) Thyrotropic hormone (TSH) secretion type: The main symptoms of hypermetabolism are feverishness, excessive sweating, weight loss, panic attacks and atrial fibrillation. (5) Other types of FSH and LH secretion: women exhibit menstrual disorders and infertility, and men exhibit male hypogonadism and infertility. The above conditions can occur alone or as a mixed tumor with increased secretion of two or more hormones, and the clinical manifestations also have corresponding mixed symptoms. 2. headache: mostly caused by increased cranial pressure or tumor stimulation. 3.Visual field disorders: mostly vision loss and bilateral temporal visual field defects. 4.Other neurological and brain damage: uveitis, hypothalamic dysfunction, high cranial pressure, cerebrospinal fluid leakage, III, IV, V-1, VI nerve palsy, etc. Diagnosis Head CT or MRI plain scan with enhancement, pituitary hormone and other examinations can be clearly diagnosed. Treatment Minimally invasive surgical treatment via nasal butterfly microscopy or endoscopy. Prognosis Pituitary tumors are benign tumors with good prognosis.