1. Do I have to use medication for pediatric epilepsy? A: Whether to start antiepileptic drug treatment after the first seizure in children needs to consider the cause of epilepsy, seizure type, epilepsy syndrome, etc. For example, after the first cluster seizure in benign infantile epilepsy, antiepileptic drugs can be temporarily not used and continue to be observed, and then start antiepileptic drug treatment if the interval is 24 hours again. For example, children with benign epilepsy with central temporal spikes and long intervals of recurrence are not necessarily in a hurry to use antiepileptic drugs, and even some children have only 1-2 seizures in their lifetime, and overtreatment of such children will do more harm than good. 2, some parents are worried about the side effects of drugs, even if the doctor lets take medication, are reluctant to give their children medication. What will happen if I don’t take the medication? A: In general, epilepsy needs to be diagnosed and treated early. This is because repeated multiple seizures, especially prolonged full-blown seizures, may damage brain function and may further affect normal brain development in developing pediatric patients. For some severe epileptic syndromes, such as infantile spasms, it is even more important to control epileptic activities as soon as possible, only then can the harm caused by epileptic activities be reduced as much as possible. 3.At present, what are the main drugs used to treat pediatric epilepsy? A: At present, the traditional anti-epileptic drugs commonly used in China are: carbamazepine (CBZ), phenobarbital (PB), valproic acid (VPA), clonazepam (CZP), phenytoin sodium (PHT); new anti-epileptic drugs are: lamotrigine (LTG), levetiracetam (LEV), oxcarbazepine (OXC), topiramate (TPM). 4. In general, should I take one drug or a combination of drugs? A: Generally, the control rate of epilepsy can reach about 60% to 70% with the rational application of one antiepileptic drug. Monotherapy has the following advantages: easy to judge drug efficacy and adverse effects; no drug interactions; relatively few adverse effects; simple program and good compliance; and light economic burden. For patients who have switched to two or three antiepileptic drugs and still cannot control their seizures after the dose and blood concentration have reached a high level or have multiple seizure types that are predictive of refractory epilepsy, an appropriate combination of drugs can be administered. The more types of drugs used in combination, the more complex the interactions. It is recommended that two to three drugs be used in combination therapy. 5. How long do I need to take medication in general? Is it possible for some children to stop taking medication at puberty? A: After antiepileptic drug treatment, about 60% to 70% of epileptic patients can achieve seizure-free. Usually, if a patient on antiepileptic medication remains seizure-free for more than two years, there is a possibility of medication reduction; for the presence of structural brain abnormalities or some special syndromes (such as JME) it should be extended to 3~5 years seizure-free. For a few age-related epilepsy syndromes (e.g., BECT), drug reduction can be considered beyond the age of onset of the disease.