Nowadays, more and more people understand the huge health risks of smoking, and quitting smoking has become the goal of many smokers. But in fact, how many people can quit smoking? The addiction is tangled, repeated failure to quit, is it really “difficult to quit smoking”? For those who quit smoking, they attribute their failure to a lack of perseverance and believe that if they have the perseverance, they will be able to quit smoking. So now it is pointed out that “this idea is not entirely correct.” Foreign epidemiological statistics show that more than 60% of smokers say they intend to quit within the next six months, more than 70% have tried to quit at least once before, and about 46% try to quit every year. However, despite a strong desire to quit, less than 3% of those who try to quit are able to stick with it for more than a year after they quit. With such a serious disproportion, it is clear that perseverance is not a major factor in quitting. Most scholars now believe that the reason why it is difficult to persist in quitting smoking is because of the withdrawal symptoms produced by smokers’ dependence on nicotine: psychological withdrawal symptoms such as depression, irritability, and lack of mental focus, as well as physical discomfort such as nausea and headache, which almost all quitters have experienced. These reactions are collectively referred to in medical terms as nicotine withdrawal syndrome, commonly known as smoking cessation syndrome. As a result, only a minority of smokers actually quit completely the first time they quit, and most smokers experience relapse after quitting. Smoking and lung cancer prevention and control strategies Every November is Global Lung Cancer Awareness Month, and one of the key themes is to focus on tobacco taxation and lung cancer prevention and control. Recent national and international data show that smoking is a major risk factor for lung cancer. Staying away from tobacco can prevent lung cancer. It is worth paying attention to: the low age of smokers has led to younger lung cancer incidence and death, more than 80% of young and middle-aged people with lung cancer symptoms are clinically diagnosed at an advanced stage when they visit the clinic, and many smokers are still not alert to lung cancer when they have breathing symptoms caused by lung cancer, which delays the time of treatment. In addition, the smoking rate among young Chinese women has been increasing significantly over the past two decades, and it is expected that the incidence of lung cancer and death among women will continue to rise in the next 30-40 years. Smokers with lung cancer have a significantly higher risk of thoracic surgery and post-surgical complication rates than non-smokers with lung cancer, and are significantly less effective at chemotherapy and molecularly targeted drugs than non-smokers with lung cancer. Smokers should take a high priority and be actively involved in keeping children and adolescents away from tobacco! Physicians should actively participate in tobacco control efforts, take the initiative to promote the health hazards of smoking, take the initiative to admonish smoker patients to quit smoking, and instruct smoker patients on how to quit smoking. Smoking and cardiovascular system disease Smoking is closely related to cardiovascular system disease, and the most effective means of preventing cardiovascular system disease is to quit smoking. Smoking is an important risk factor for cardiovascular disease and hypertension in the Chinese population, with male smokers living an average of 13.2 years shorter than nonsmokers and female smokers living an average of 14.5 years shorter than nonsmokers. 33.5% of deaths due to smoking are due to cardiovascular disease, with smoking promoting the formation and progression of atherosclerotic plaques, increasing the risk of myocardial infarction increasing the risk of death from coronary heart disease, and increasing the risk of increased risk of sudden cardiac death. The most effective way to prevent cardiovascular disease is to quit smoking. Smoking cessation begins with refusing the first puff Tobacco is the largest preventable pathogenic factor that physicians face in their careers, and tobacco dependence is a chronic disease that warrants aggressive treatment and requires repeated interventions. It is also noted that cigarettes are the most effective device in existence for transmitting nicotine, superior to intravenous injections cigarettes are only the outer packaging, the real product sold is nicotine a pack of cigarettes is like a container containing a day’s amount of nicotine a cigarette is like a drug delivery device containing a unit dose of nicotine. The best solution for tobacco dependence: a combination of medication and behavioral therapy, varenicline, recently marketed in the United States and Europe to help adult smokers quit, was approved by the Chinese SFDA on July 31, 2008 and will be available in China in December. Varenicline is available in 0.5 mg and 1 mg dosage forms, and treatment is initiated 1 to 2 weeks prior to the quit date for a 12-week course of treatment, or for an additional 12 weeks while dose reduction is considered. Side effects include insomnia, nausea, gastrointestinal distention, and constipation. To date, no other clinical intervention has been as effective in reducing the incidence of disease, preventing death, and improving quality of life as interventions for tobacco dependence. Finally, we offer the hope that non-smokers: refuse the first puff! Smokers: Quit successfully! Quitters: Don’t buy cigarettes! Do not pick up cigarettes! No second-hand smoke!