(Disclaimer: This article is only for popularization purposes, and the information in the following content has been processed in order to protect the patient’s privacy) Abstract: A 69-year-old female patient with a history of hypertension, diabetes mellitus, and atrial fibrillation suddenly experienced symptoms of chest tightness and panic attacks after square dancing 2 days ago, and sought medical attention in time for fear of aggravation of her primary disease. After the patient was examined, she was admitted to our hospital with permanent atrial fibrillation, and was prescribed oral medication to alleviate her symptoms, and was instructed to monitor her heart rate and blood pressure on a daily basis and to undergo regular checkups. Basic information] Female, 69 years old [Type of disease] Permanent atrial fibrillation [Hospital] The First Affiliated Hospital of Xi’an Jiaotong University [Date of consultation] December 2021 [Treatment plan] Oral medication (Rosuvastatin calcium tablets, propranolol hydrochloride tablets, rivaroxaban tablets, metoprolol tartrate tablets, metformin hydrochloride tablets, acarbose tablets, daglitazar tablets, indapamide extended-release tablets) [Therapy Periodicity] 6 days of hospitalization, 2 weeks of follow-up, long-term follow-up [Treatment effect] Chest tightness, panic symptoms disappeared, condition stabilized I. Initial interview When I first saw the patient, she had a slow gait, an open-mouth breathing face, and shortness of breath. The patient’s family said that she had a history of hypertension, diabetes mellitus, and atrial fibrillation, and had been taking medication regularly, because she suddenly developed chest tightness and panic symptoms after square dancing two days ago, which had not been relieved, and because she had not taken much of her long-standing oral medication, and had not been taking medication regularly for two days, so she wanted to see a doctor to check on her condition and to prescribe some medication. I carried out a general examination for the patient and found that his heart rate was 125 beats per minute, blood pressure was 153/112 mmHg, and the patient’s respiratory sounds were coarse in both lungs, with no dry or wet rales detected; there was no edema in both lower limbs; the electrocardiogram showed atrial fibrillation and ST-T segment changes. Combined with the above findings, the patient was initially diagnosed with permanent atrial fibrillation and was admitted to the hospital for treatment. Because the symptoms were mild, conservative treatment was considered to achieve ideal results. After communicating with the patient and his family, a symptomatic supportive treatment program of improving circulation, anticoagulation and lipid regulation was given to improve his symptoms. The patient was prescribed Rosuvastatin calcium tablets, which can reduce fat and stabilize plaque, and propranolol hydrochloride tablets to improve myocardial oxygen consumption and promote the relief of chest tightness and other uncomfortable symptoms; the use of anticoagulant rivaroxaban tablets, to prevent thrombosis; because of the patient’s own rapid heart rate, the patient was instructed to take metoprolol tartrate tablets to control the ventricular rate, supplemented with metformin hydrochloride tablets, acarbose tablets, and daglitazar tablets to control the level of blood glucose, the indapamide extended-release tablets. Indapamide extended-release tablets were used to stabilize blood pressure. After 6 days of regular oral medication, the patient’s chest tightness was basically relieved without chest pain and nausea and vomiting, and the current examination: consciousness was clear, spirit was available, the breath sounds of both lungs were coarse, and no dry and wet rales were heard; heart rate was 100 beats/minute, arrhythmia, and no pathologic murmur was heard in each valve auscultation area; the abdomen was soft with no pressure pain and rebound pain, and the liver, spleen, and subcostal area were not detected; the double lower limbs had no edema. The patient recovered well, and was discharged from the hospital, continuing to take the above medications orally, and reviewing in the outpatient clinic after 2 weeks. Precautions Because the patient had discomfort symptoms in time to seek medical treatment, oral medication symptoms better relief, I sincerely feel happy for the patient, advised the patient to pay attention to the following matters: 1, daily to avoid emotional fluctuations, so as not to lead to elevated blood pressure triggered by other underlying diseases; 2, at home should be regular monitoring of blood pressure and blood glucose, if there is a loss of control of the phenomenon should be promptly consult a doctor, to avoid adjusting their own therapeutic drugs; 3, should ensure a light diet, avoid eating too much food, and should not be too much food. Ensure a light diet, avoid eating high sugar, high fat, greasy and spicy food, to promote the body to maintain a healthy state; 4, after discharge from the hospital, follow the doctor’s instructions to take medication regularly, do not increase or decrease the dosage of medication due to the improvement or aggravation of symptoms. The patient belongs to the group of people who love to dance, because of the discomfort after strenuous activities, but because of the strong sense of medical care, early and timely after the emergence of uncomfortable symptoms, through the oral medication can be a better control of the symptoms. Therefore, it is recommended that the elderly who are more active in daily life should actively consult a doctor after experiencing symptoms such as palpitations, dizziness, chest tightness, and fatigue, so as to have a clear diagnosis after relevant examinations, which can facilitate the formulation of a treatment plan, shorten the course of the disease, and improve the prognosis.