Cholestatic urticaria can be clinically cured through treatment, but complete eradication is more difficult. Cholinergic urticaria is mainly related to factors such as elevated body temperature in the local center of the skin, and common triggers include hot baths, exercise, eating spicy food, etc. It manifests itself as a round, pimply, windy bump on the surface of the skin, accompanied by severe itching, tingling sensation or burning sensation. Cholinergic urticaria symptoms are mild, when the triggering factors are avoided, usually within minutes or hours of self-cure, moderate and severe patients actively medication, can also achieve clinical cure, but when the organism is again exposed to the triggering factors, there is a possibility of relapse, so that the condition is recurrent and difficult to cure. Cholestatic urticaria patients daily to maintain a cooler body temperature, avoid emotional stress, avoid eating spicy stimulating food, reduce exercise, etc., can prevent the occurrence of cholestatic urticaria.