(Disclaimer: This article is for scientific purposes only. In order to protect the patient’s privacy, the relevant information in the following content has been processed.) Abstract: The case patient is a 54-year-old female. The patient reported that she had neck pain after diarrhea, accompanied by chills, fever, headache, numbness and weakness of both lower limbs, and lumbar pain, and so on, and so she came to the hospital. After physical examination, whole spinal cord magnetic resonance and lumbar puncture examination, he was diagnosed with transverse myelitis. After medication was given, the symptoms of numbness in the limbs and trunk were relieved. Basic information] Female, 54 years old [Type of disease] Transverse myelitis [Hospital] The Second Affiliated Hospital of Harbin Medical University [Date of consultation] January 2022 [Treatment plan] Medication (Vitamin B1 tablets + methylcobalamin tablets + Mannitol injection + Methylprednisolone tablets + Moxifloxacin hydrochloride tablets) + Psychological counseling [Period of treatment] Inpatient treatment for 10 days, followed by regular follow-up visits after 1 month 【Treatment effect】 Limbs and trunk numbness relieved. Therapeutic effect] Numbness of limbs and trunk relieved I. Initial consultation The patient was a farmer, who had neck pain after diarrhea for 7 days before admission, accompanied by chills, and complained of fever with headache without special attention, and numbness and weakness of both lower limbs for 3 days before admission, which started from numbness and weakness of the right lower limb to numbness of the left lower limb, and was accompanied by numbness of the chest with lumbar pain for one day before admission, in order to make a clear diagnosis and treatment. The patient was given complete whole spinal cord magnetic resonance, lumbar puncture and other examinations, and was admitted to the hospital. After admission, the patient’s examination showed that there were no significant signs on cardiopulmonary examination, and specialized examination showed that the muscle strength of bilateral lower limbs was grade 4, and the superficial and deep sensations below the chest 4 plane were reduced, and pathological reflexes were not induced. Total spinal cord magnetic resonance examination showed that a slightly longer T2 signal was seen in the cervical and thoracic spinal cord, and spondylitis was considered. Lumbar puncture examination showed: cerebrospinal fluid sugar 2.36mmol/L, cerebrospinal fluid chloride 122.0mmol/L, cerebrospinal fluid pressure 138mmH2O, cerebrospinal fluid albumin 501mg/L, and cerebrospinal fluid cell count 6. Combined with the patient’s symptoms and the examination results, he was diagnosed with transverse myelitis. After communicating with the patient about his specific condition, the patient expressed his willingness to actively cooperate with the treatment. Subsequently, the patient was given vitamin B1 tablets, methylcobalamin tablets for nerve nutrition, mannitol injection for dehydration to relieve spinal cord edema, methylprednisolone hormone for gradual reduction of treatment after impact, moxifloxacin hydrochloride tablets for anti-infection, as well as psychological counseling and comfort. Third, the effect of treatment After 10 days of drug and psychological comfort treatment, the patient’s limb numbness and trunk numbness symptoms alleviate obvious, hormone from static to oral, and slowly reduce the amount, the patient’s bilateral lower limb muscle strength 5-grade, speech fluent, sensory plane down to the chest 12, the mental outlook is also better, the patient was discharged, and asked the patient to be regularly rechecked in the clinic in 1 month. The patient was discharged from the hospital and was advised to have regular outpatient review for one month. It is recommended that the patient still needs to pay attention to maintenance after discharge, avoid cold and flu, pay attention to rest, avoid staying up late, tired and nervous, etc., and pay attention to keep the bowel movement smooth. In daily diet, patients should pay attention to light diet, avoid spicy and stimulating food, and maintain a healthy lifestyle. Fifth, personal feelings Transverse myelitis patients, some cases will have fever, general malaise or upper respiratory tract, gastrointestinal tract infection, vaccination history, can be triggered by fatigue, trauma, cold, and mental stimulation. As the disease is different, the prognosis varies greatly. Patients with symptoms such as chest and waist girdle sensation, accompanied by limb weakness and numbness, must go to the hospital for examination as soon as possible, so as not to develop into a serious disease. The patient in this case was fortunate in that he did not seek medical attention in time when symptoms appeared, but his condition was relieved with medication and other treatments.