Patient: 48, previously in good health. He was admitted to Liuzhou People’s Hospital for 34 days due to a fever with a maximum temperature of 39 degrees, followed a few hours later by persistent swelling and pain in the left arm with paroxysmal increase of pain from the left arm to the posterior side of the left calf, with numbness in the posterior side of the left calf. He was given intravenous penicillin to fight against infection, and finally discharged after 21 days of injection with anti-drug reaction and discontinuation of injection and 10 days of oral penicillin solution with anti-drug reaction and discontinuation of injection. At the time of discharge, the indexes were ultrasensitive c-reactive protein 5,97mg/l, computerized dynamic sedimentation 35mm/h, white blood cell count 6,30*10^9l, lying in bed for 90 days without getting out of bed, feeling numbness in the left leg and a hard lump in the left lumbar region. I just had an MRI and blood test results: l5/s1 disc degeneration protrusion, left lateral saphenous fossa stenosis, nerve root compression, consider combined discitis, ultrasensitive c-reactive protein 21, 33mg/l, computerized blood sedimentation 23mm/h, white blood cell count 5, 67*10^9l, the treatment effect is not ideal what is the cure doctor: Hello septic spinal infection treatment is very tricky. The first is to find the source of the infection and the infecting bacteria. You can repeat several blood cultures or puncture fluid culture to clarify the type of infecting bacteria and drug sensitivity. 2, antibacterial drugs should be adhered to long-term, adequate application. Do not stop drug treatment just in time 3, pay attention to the protection of the lumbar spine. Due to the infection, it will lead to the destruction of bone structure, try not to weight-bearing activities, there is a risk of collapse of the vertebrae, and even lead to nerve damage. It is recommended that bed braking is the main, really need to go down, need to strictly wear support. 4, conservative treatment is not effective, nerve damage changes, need to be decisive, surgical treatment.