Spinal cervical spondylosis (CSM) is a progressive degenerative disease of the spine and the most common cause of spinal cord damage in adults worldwide. In this age group, 70-95% of the population has an imaging of osteophytes that may compress the spinal cord. The incidence and extent of exacerbation are not known. The treatment of CSM is controversial, with only one randomized controlled trial (RCT) to date showing conservative and surgical equivalence, but this RCT has limited power; multicenter, prospective studies have confirmed that surgery can halt CSM progression and improve function and quality of life, however, this finding is limited to patients in North America, and the short- and medium-term efficacy of CSM surgery needs to be studied globally. A prospective, multicenter study led by Professor Michael at the University of Toronto, Canada, and conducted by scholars at the AOSpine Center worldwide, suggests that surgical decompression for spinal cervical spondylosis is safe and effective, and was recently published in Spine. The study included 479 patients with symptomatic, imaging-confirmed CSM and initial surgery at 16 AOSpine spine centers from October 2007 to January 2011. symptoms of CSM included hand numbness, clumsiness, abnormal gait, weakness, and sensory abnormalities in both upper extremities. The type of surgery (anterior, posterior, or combined anterior and posterior), surgical segment, and type of internal fixation were determined by the surgeon. Assessments included preoperative and postoperative general condition, functional impairment and quality of life on a modified JOA (mJOA) score (0-18), Nurick score (spinal cord function, 0-5, with 0 being the best and 5 the worst), Neck Disability Index NDI (modified version of ODI), and SF36 2nd edition. The results at preoperative, 12-month, and 24-month postoperative follow-ups were analyzed. The results showed that the patient cohort consisted of 310 men and 169 women with a mean age of 56.37 years. Differences in age, etiology, and surgical access were observed among patients from different regions. The mean duration of disease was 27 months, and the most common approach was anterior (55.74%), followed by posterior (39.96%), and anterior-posterior combination only accounted for 2.3%. The average number of fused segments was 3.66, and the most common decompressed segments were C4 (73.7%), C5 (92.69%) and C6 (87.27%). Twenty-four months after surgery, mJOA improved from 12.50 to 14.90 preoperatively, NDI improved from 36.38 to 23.20, physical score (PCS) improved from 34.28 to 40.76 and thought score (MCS) improved from 39.45 to 46.24 in SF36 version 2. The incidence of neurological complications was 3.13%: 9 patients had C5 or new-onset upper extremity pain ( The rate of neurological complications was 3.13%: C5 or new upper limb pain in 9 patients (1.88%) and worsening spinal cord lesions in 6 patients (1.25%). The postoperative infection rate was 3.34%, 80% of which were superficial infections. Improper nail placement 1.04%, internal fixation failure 0.84%, and bone graft displacement 0.21%. This study is the largest prospective study and the first report of global CSM surgical outcomes. Prospective studies of global cases have shown that surgical decompression is safe and effective in CSM, with improvement in patient function and quality of life, independent of health care system and sociocultural factors, and is maintained into the short and medium term with a low complication rate.