Azithromycin belongs to the macrolide class of antibiotics and is mainly used for the treatment of mycoplasma pneumonia. If a patient is diagnosed with mycoplasma pneumonia, it can be basically cured by treating with azithromycin infusion for about one week. Patients presenting with cough, coughing sputum, afternoon fever, and blood in sputum symptoms can disappear significantly, and dry and wet rales in both lungs can be heard on physical examination are also significantly absorbed. Chest imaging suggests scattered patchy shadows in both lungs, indicating the presence of bronchopneumonia. These symptoms and signs examination can be obviously improved, indicating that mycoplasma pneumonia is basically cured after one week of azithromycin treatment. However, azithromycin alone can easily produce certain drug resistance. It needs to be combined with routine blood tests to understand whether there is a combination of bacterial infection and whether additional penicillin or cephalosporin antibiotics are needed to avoid recurrence of the disease. The majority of mycoplasma pneumonia can heal on its own, but it can also recur during the treatment process, so it needs to be analyzed on a case-by-case basis.