Because there is no cure for essential hypertension, patients should adhere to long-term medication, and they should regularly observe the efficacy and adverse effects of the medication. Patients with hypertension should also pay attention to some issues when taking medication. 1, gradually lower the blood pressure, because the blood pressure is lowered too quickly, too violent will make the patient’s brain and kidney blood supply is inadequate, resulting in a series of symptoms, especially the kidneys can not tolerate too low changes in blood pressure, so there must be an adaptation process. 2, the variety and dose of medication should vary from person to person. 3, combined medication is better than high-dose single drugs. Some patients, when inquiring about a certain antihypertensive drug treatment effect, only choose this one drug treatment, the result of taking medication for a long time, and blood pressure is still high, this is a problem that should be paid special attention to. The application of any one antihypertensive drug alone can only bring blood pressure down to normal values in 60% to 70% of patients with hypertension. Therefore, when the blood pressure is very high, it is best to use two or more antihypertensive drugs with different mechanisms of action. 4, do not suddenly stop or suddenly reduce a drug, even if the drug alone is not effective. 5, patients and their families should understand and master the knowledge of using several drugs, such as understanding that captopril and other high blood pressure can lower blood pressure, but not lower normal blood pressure, and can be taken sublingually. 6, the choice of diuretic antihypertensive drugs must be added to take potassium-containing drugs to prevent low blood potassium. Some compound antihypertensive drugs also contain diuretics (such as indapamide is also a diuretic antihypertensive drugs), should also be supplemented with potassium. 7, after choosing a good treatment plan in a certain period of time, it is best not to change the plan, should accept the doctor’s patient education, persistently adhere to treatment.