Acetaminophen can cause rash, urticaria, drug fever and granulocytopenia. Long-term heavy dosing can lead to abnormal liver and kidney function. Overdose of acetaminophen is an important cause of fulminant liver failure. Chlorpheniramine maleate can cause drowsiness, thirst, polyuria, sore throat, sleepiness, feeling of weakness, palpitations, skin petechiae, and bleeding tendencies. Caffeine is a psychostimulant that counteracts the central sedative effect of chlorpheniramine maleate, but long-term heavy use can cause addiction, gastrointestinal discomfort, psychological confusion, anxiety, and rapid heartbeat. Artificial cowberry is a traditional Chinese medicine with detoxifying effects and fewer side effects, and should be used with caution in patients with renal insufficiency. The combination of ingredients together sometimes causes mild dizziness, weakness, nausea, epigastric discomfort, dry mouth, lack of appetite and skin rash, which can recover on its own. You should not take other anti-cold drugs similar to this product at the same time, and you should not drive machines, vehicles, boats, engage in high-altitude work, mechanical work and operate precision instruments during the period of use. And do not drink alcohol or drinks containing alcohol during the medication.