Acne is mainly caused by high androgen levels during adolescence, or by diseases such as polycystic ovary syndrome or cortisolism that lead to endocrine disorders and increased androgens, as well as a dusty working environment and lack of attention to facial cleanliness, etc. This causes excessive sebum production on the nose, which clogs the pores and leads to acne. This is manifested as enlarged pores and can be squeezed with a white, longer, or bean residue-like discharge.