Urticarial vasculitis does not heal on its own and is an autoimmune disease that may be associated with infections, drugs, and tumors. It is mainly treated by drugs, and plasma exchange is needed if the condition is serious. 1. Drug therapy: commonly used drugs include glucocorticoids, antihistamines, immunosuppressants, ampicillin, non-steroidal anti-inflammatory drugs, antiviral drugs and so on. (1) Glucocorticosteroids: for example, prednisone, prednisolone, etc., are used to reduce the inflammatory response of the skin and reduce vascular inflammation. (2) Antihistamines: e.g., loratadine, etc., are used to reduce the patient’s itching symptoms. (3) Immunosuppressants: for example, cyclophosphamide, etc., used to reduce the inflammatory response of the skin. (4) Amphetamine sulfone: for example, Amphetamine sulfone tablets, which are used to reduce the patient’s skin lesions. (5) Non-steroidal anti-inflammatory drugs: such as ibuprofen, used to reduce pain due to vasculitis. (6) Antiviral drugs: for example, ribavirin, which is used to fight viruses and reduce the patient’s infection. 2. Plasma replacement: Reduce inflammatory factors in the blood through plasma replacement to reduce vascular inflammatory reaction, applicable to patients with frequent and severe attacks. If the diagnosis of urticarial vasculitis is confirmed, it is recommended to consult a doctor in time, and under the guidance of the doctor to formulate an appropriate treatment plan, and actively cooperate with the treatment. The medication should be used according to the doctor’s prescription.