Comprehensive treatment is the cornerstone of tumor treatment

Malignant tumor is a common and frequent disease that seriously threatens human health. 2012 China Tumor Registry Annual Report reported that there are about 3.12 million new cases of tumor in China every year, averaging 8550 people per day. The clinical efficiency of tumor has been improved year by year, but the result is still unsatisfactory. At present, the number of deaths caused by tumor has surpassed cardiovascular disease and become the number one killer of human beings, which shows that human beings have a long way to go to overcome malignant tumor. Comprehensive treatment is the cornerstone of tumor treatment. Surgery is an important means of tumor treatment, about 60% of tumors are treated by surgery as the main means, and surgery is also a diagnostic and staging tool for 90% of tumors. For most of the early stage tumors without metastasis, surgery can often achieve the purpose of radical cure. If the cancer is in the middle and late stage and the cancer cells have spread in the body, then palliative surgery can slow down the growth of tumor and improve the quality of survival of patients in the late stage, or provide better conditions for other treatments. 2.Radiotherapy is a kind of local treatment to kill tumor cells by irradiating the tumor area with radiation to the maximum. At present, about 60%-70% of tumor patients need radiotherapy in different periods of the disease process. The most common methods of radiotherapy are external irradiation, internal irradiation, including inter-tissue particle implantation radiotherapy, and other radioisotope internal radiotherapy. 3.Chemotherapy Modern chemotherapy for tumors started in 1960s. It is a method of using chemical drugs to inhibit or kill tumor cells, which belongs to the systemic treatment of tumor. Almost all tumor patients can undergo chemotherapy at different stages of treatment. At present, there are many types of chemotherapy drugs, and with the development of medicine, chemotherapy is gradually changing from single drug to combination chemotherapy, and from palliative treatment to radical treatment. In the era of comprehensive tumor treatment concept, chemotherapy is also an adjuvant treatment method to surgery or radiotherapy. Chinese medicine is the summation of practical experience, which is the valuable experience of thousands of years of human beings fighting against diseases. In treating diseases, TCM emphasizes the holistic concept and evidence-based treatment. TCM treatment for tumors restores and enhances the patient’s own resistance to disease through overall adjustment, two-way adjustment, self-adjustment and functional adjustment, so as to achieve the balance of yin and yang for the purpose of treating diseases, and TCM plays an important role in the comprehensive treatment of malignant tumors. 5.Biological therapy Tumor biological therapy can directly regulate the growth and differentiation of malignant tumor; promote the transformation of cancer cells from low differentiation to high differentiation; improve the sensitivity of human immune function to cancer cells and facilitate the killing. The best time for biological therapy in the comprehensive treatment of tumor is to kill a large number of tumor cells through surgery or radiotherapy first, and then to kill or inhibit the remaining tumor cells through activating the biological effect of immune system to achieve the purpose of radical cure. With the development of medical science, biological immunotherapy will become an effective means of tumor treatment and can be applied to most cancer patients. The combination of Chinese and Western medicine has its own advantages and disadvantages in treating malignant tumors. The combination of Chinese and Western medicine is more effective than Chinese medicine or Western medicine alone in treating tumors, because Chinese medicine can make up for the shortage of Western medicine to a certain extent, while the advantages of Western medicine are the weakness of Chinese medicine. Organic combination of western medicine treatment and Chinese medicine treatment can recognize the advantages and shortcomings of Chinese medicine and absorb the essence of western medicine, so as to complement the strengths and improve the efficacy of comprehensive treatment with western medicine. 1, Chinese medicine and surgery patients preoperative taking beneficial qi, spleen and other corrective Chinese medicine, can improve the function of certain organs of the patient, enhance physical fitness, to create good conditions for surgery; and most patients have postoperative weakness, weakness, constipation and other deficiencies of qi and blood performance, taking tonification of qi and blood, strengthening the spleen and stomach Chinese medicine treatment, can reduce the complications of surgery, restore the patient’s physical fitness, trying to avoid or reduce metastasis and recurrence, improve the long-term The effect of Chinese medicine and radiotherapy 2.Chinese medicine and radiotherapy can reduce the toxicity of radiotherapy by nourishing yin and nourishing fluid, clearing heat and detoxifying herbs (such as princeton ginseng, American ginseng, genetic ginseng, maitake, raw earth, chasteberry, dendrobium, smallpox powder, white flowered snake’s tongue grass, half branch lotus, etc.), which can reduce the toxicity of radiotherapy, that is, play a role in reducing the toxicity; and the addition of beneficial qi, spleen and qi herbs can also enhance the efficacy of radiotherapy, that is, play a role in increasing the sensitivity or effectiveness of radiotherapy. 3.Chinese medicine and chemotherapy can enhance the anti-cancer effect of chemotherapy, which can significantly prolong the survival period compared with chemotherapy alone. Taking Chinese medicine during chemotherapy can reduce the adverse reactions of chemotherapy, such as gastrointestinal reactions, which are often used to strengthen the spleen and stomach, benefit the qi and support the righteousness; between chemotherapy, by nourishing the spleen and stomach, can improve the patient’s constitution, improve the bone marrow hematopoietic function, and prepare for the next chemotherapy; after chemotherapy, taking Chinese medicine is mainly to improve the long-term efficacy and reduce recurrence and metastasis. 4. Chinese medicine and biological therapy are commonly used in Chinese medicine, such as ginseng, astragalus, safflower and salvia, as well as Xiao Chai Hu Tang, Ten Perfect Tonic Soup and Six Flavored Di Huang Tang, which have the effect of enhancing the immunity of the body and regulating the biological function to suppress tumor, which are very similar to the biological therapy in Western medicine. For biological treatment of advanced cancer, many experts suggest that it is better to combine multiple biological agents, and the combination of traditional Chinese medicine with them can undoubtedly improve the efficacy. Minimally invasive tumor treatment is a new mode of tumor treatment, which is characterized by no incision, less trauma, fewer complications, precise positioning and safe treatment. The indications for minimally invasive treatment are patients who are not suitable for surgery, radiotherapy and chemotherapy, or patients with solid tumors that are recurrent or insensitive after surgery, radiotherapy or chemotherapy. Especially for elderly tumor patients who can’t or don’t want to operate and can’t receive radiotherapy or chemotherapy, it can give more advantage to their treatment. 1. Minimally invasive surgery: Minimally invasive treatment is performed under direct vision, in addition to minimally invasive surgery, through thoracoscopy, laparoscopy and biliary tractoscopy. The purpose is to remove the tumor. Microwave, radiofrequency and cryotherapy can also be applied to the tumor under direct vision. 2.Minimally invasive interventional treatment: Minimally invasive treatment with the help of image guidance, using ultrasound, fluoroscopy, CT, nuclear magnetic, etc., special catheters, guide wires, puncture tools and other precision instruments are introduced directly into the human body to diagnose the lesion, take biopsy or carry out local treatment. According to the route of treatment, tumor interventional therapy includes vascular intervention and non-vascular intervention. Interventional treatment of tumor has the advantages of minimally invasive, low cost, safety and good efficacy, and has become one of the important components of clinical therapeutics of malignant tumor. 3.Thermal therapy: It is to change the environment in which tumor cells are located through heating, so as to denature and necrotize tumor cells and achieve the treatment purpose. Heat therapy can be divided into two types: systemic heat therapy and local heat therapy. Systemic thermotherapy can be heated by blood circulation or by placing the body in a thermal environment. There are many kinds of localized thermotherapy, such as infrared rays, which cause local high temperature of tumor and degeneration and necrosis of tumor cells. Some advanced or locally advanced tumor patients can reduce symptoms and improve the quality of survival through thermal therapy, which can play a better role in palliative treatment. 4.Argon helium knife: using a number of space rocket guidance technology, high pressure argon gas under computer control instantly (within 60 seconds) cools down the tissue around the knife tip to about -40℃, ice crystals are rapidly formed in the cells, causing cell degeneration and necrosis; after that, high pressure helium gas expands rapidly at the knife tip, quickly thawing the ice ball and rapidly warming up to 45℃; this “hot and cold reversal therapy” is particularly effective in destroying the diseased tissues. This “hot and cold reversal therapy” is particularly effective in destroying diseased tissues, resulting in more complete cell necrosis. The necrotic cell fragments are usually absorbed in about 3 weeks. The absorbed inactivated tumor tissue has the function of regulating tumor antigen and activating tumor immune response. 5.Ultrasound Focused Knife: Using the physical characteristics of ultrasound such as focusability and soft tissue penetration, low energy ultrasound in vitro is gathered in specific target tissues in vivo, and high energy ultrasound at the focal point can produce transient high temperature over 65℃, which can kill tumor cells through thermal effect, cavitation effect and mechanical effect, causing coagulative necrosis of local target tissues to achieve treatment purpose, which is equivalent to surgery in vitro and ” cutting” the cancer block. 6.Photodynamic therapy: It uses tumor cells to selectively absorb photosensitizers, and then uses non-thermal laser of specific wavelength to irradiate the lesion area, which causes violent photochemical reaction of photosensitizers in tumor tissues, so as to selectively destroy tumor cells. 7.Laser therapy: Laser is a kind of artificial light source, which has the characteristics of small emission angle, pure spectrum, good coherence and high energy density. Laser therapy of tumor can cut bone, stop bleeding and vaporize tumor tissue because of its effect of heat, pressure, light and electromagnetic field effect on biological tissue. The methods of laser treatment for tumor include cutting, cautery, coagulation and endoscopic method. Multidisciplinary collaboration is the guarantee of comprehensive tumor treatment Multidisciplinary comprehensive treatment of malignant tumor is not the simple superposition or random combination of multiple treatment methods, the formulation of comprehensive treatment plan should be based on the patient’s physical condition, pathological type of tumor, development stage and treatment prognosis. After comprehensive analysis and full discussion and negotiation among multidisciplinary doctors, a thorough and scientific arrangement plan will be formulated to apply all available treatments in a planned and rational manner, with the aim of maximizing the cure rate and improving the quality of life of patients as much as possible. The best combination of comprehensive treatment plan requires that each treatment chosen should have the best efficacy and the least side effects when used singly. The comprehensive treatment of tumor should have the collaboration and close cooperation among the professionals of oncology, medical and surgical departments, radiotherapy, pathology, imaging, intervention, ultrasound room, nuclear medicine and other related departments in order to obtain the best effect and overcome the limitations in the understanding of each professional under the current subspecialty system and the current tumor professional training system, so that the advantages of each department can complement each other and facilitate the formulation of detailed treatment plan from the whole picture from the beginning of the patient’s treatment. In this way, it is easy to make detailed treatment plans from the beginning of the treatment, so that patients can receive the most perfect treatment. To sum up, tumor is not an individual disease, it is often a local manifestation of systemic lesions, and dissemination and metastasis may exist at any time. Therefore, the best therapeutic effect can only be achieved through multidisciplinary collaboration, combination of Chinese and Western medicine, and the use of various existing therapeutic means in a rational, scientific and planned manner.