Toxoplasmosis, a zoonotic parasitic disease caused by Toxoplasma gondii. It is widely distributed throughout the world. There are two types of infections: congenital and acquired infections. Both types are mostly asymptomatic occult infections in humans and generally do not cause serious symptoms of occult infections and generally do not cause serious sequelae. However, the clinical manifestations of the onset of the disease are extremely complex and often vary depending on the infected organ, mainly invading the eye, brain, lymph nodes and heart, causing chorioretinitis, hydrocephalus, microcephaly, ocular hypermetropia and cerebral calcification. The diagnosis of the disease is confirmed by specific serum immunological tests. There are many reports of toxoplasmosis abroad, and in recent years, attention has been paid to it in China. Almost all mammals, including cats, rabbits, pigs and dogs, have been found to be naturally infected with Toxoplasma gondii, with cats having the greatest rate of infection because the oocysts of Toxoplasma gondii excreted in cat feces can exist in the outside world for a longer period of time posing a threat of infection. The disease is closely related to pregnancy. The prevalence of Toxoplasma gondii infection in pregnant women has been reported to be 0.26% in Tokyo, 0.8% in Paris, and 0.36% in New York, with a fetal infection rate of 34%-40%. It is assumed that the infection rate of pregnant women and fetuses in China will not be lower than this figure. After a mother is infected with Toxoplasma gondii during pregnancy, whether it is a dominant or recessive infection, it can infect the fetus through the placenta, directly affecting fetal development and causing serious malformations. In addition, almost all cats, dogs, sheep and chickens have Toxoplasma gondii in their organs, and those who have eaten uncooked dogs, drink unsterilized milk and raw eggs can also be infected. Prevention and health education should be carried out to raise people’s awareness of toxoplasmosis; improve environmental hygiene, strengthen the management of water sources, feces and livestock, especially to prevent cat feces from contaminating food, feed and water sources; blood donors should be tested for serum toxoplasmosis antibodies; do not eat raw meat or uncooked meat and chicken and duck eggs, and avoid close contact with cats, dogs and other animals as much as possible; all slaughterhouses and meat processors should be properly prevented and regularly inspected. The slaughterhouse and meat processing personnel should do a good job of prevention and regular inspection. Women of childbearing age and pregnant women should undergo serological examination of Toxoplasma gondii antibodies. If only positive for Toxoplasma IgM occurs in early pregnancy, the pregnancy should be terminated; if it occurs in the middle or late pregnancy, spiramycin should be given as oral treatment.