Let the tumor take a hot bath

Tumors often metastasize to the peritoneum at advanced stages of development, forming metastases one by one. It is just like a farmer planting and sowing seeds, but the tumor as seeds produced is not what we hope for. In the past, when peritoneal implantation was found during surgery, the death sentence was often pronounced, and the struggle with tumor was ended early. With the advancement of time, technological innovation, in-depth research and change of philosophy, the battle against tumor with peritoneal implantation has just begun. Peritoneal implantation is mostly caused by metastatic implantation of stomach cancer, colorectal cancer and other abdominal organ tumors. At present, while actively treating the primary tumor, there are numerous techniques to treat peritoneal metastases. Currently, peritoneal implantation found during surgery can be treated by tumor cytoreductive surgery (CRS) plus heat-infused peritoneal chemotherapy (HIPEC). Micro-metastatic cancer and free cancer cells in the abdominopelvic cavity are removed by surgical excision of the lesion visible to the naked eye, followed by peritoneal heat infusion chemotherapy. It has been found that tumor will increase cell membrane flow at 43°C, leading to collapse, while supplemented with chemotherapeutic drug combination therapy to increase the contact surface of drugs with peritoneum and increase the local drug concentration, thus reducing or decreasing the toxic side effects of drugs, which can kill the residual tumor cells to the maximum extent. Especially for the diseases with extensive peritoneal implantation, such as appendiceal pseudomucinous tumor, it can even achieve cure. The tumor can be killed unconsciously like a frog boiled in warm water. The clinical experience of our center in recent years shows that the efficacy of this technique is closely related to the disease type, and the efficacy of peritoneal implantation or metastasis of colorectal cancer is much better than other tumors with peritoneal implantation. The multidisciplinary diagnosis and treatment of bowel cancer in our hospital has prolonged the survival and improved the quality of life for many patients with locally advanced bowel cancer and recurrent bowel cancer by hybridizing the use of several techniques including warm infusion. This has led to greater confidence and a more positive attitude towards the treatment of advanced bowel cancer.