Many patients are afraid of surgery, coupled with the fact that surgery requires routine hospitalization, which takes about 7-10 days, and has a large one-time cost, and often hope to cure deviated septum by simple medication. At the same time, the overwhelming advertisements and certain so-called reports in the name of news from various newspapers, TV and internet, driven by various interests, are constantly misleading people. However, nasal septal deviation is a deviation of bone or/and cartilage, and it is impossible for drugs to change the morphological abnormality of bone and cartilage. Simple drug treatment can only temporarily relieve symptoms such as nasal congestion, bleeding and headache to a certain extent, but it is impossible to completely eliminate various related symptoms caused by abnormal nasal septum morphology. Moreover, once the nasal septal deviation is accompanied by long-term or/and severe nasal congestion symptoms, it indicates that the adjustment function of inferior turbinate begins to lose compensation, and if not corrected in time, the loss of compensation will become more and more serious. To improve the symptoms and recover completely, septal surgery is often difficult to avoid. In conclusion, medication is unlikely to change the deviated nasal septum and, at least for now, there is no evidence that medication can replace surgical treatment.