Many patients think that there is no good treatment for epilepsy at present after a long-term treatment effect, in fact, there are reasons why most epilepsy treatment fails, here are a few reasons why epilepsy treatment fails. The diagnosis error To achieve the ideal treatment effect of any disease, a clear diagnosis is very important, if there is no clear diagnosis, the effective treatment is not possible. Diagnostic errors in epilepsy include misdiagnosis and misjudgment of seizure type. Some patients diagnosed with epilepsy are not epileptic at all, but other patients, including non-epileptic seizure disorders, such as hysteria, extrapyramidal disorders, and sleep disorders; misjudgment of seizure type can directly lead to errors in treatment, because the selection of antiepileptic drugs is mainly based on seizure type, and when the wrong drug is selected, it not only cannot relieve seizures but also may aggravate them. Some antiepileptic drugs can aggravate seizures, such as carbamazepine and phenytoin sodium. The most important thing is to find the best dose of medication according to the principle of individualization, through efficacy observation and blood concentration monitoring. Some drugs poisoning make seizures become frequent and lead to drug-derived seizures, but they are often misjudged as insufficient dose and blindly increased, such as phenytoin sodium poisoning. Some people like to treat epilepsy with a combination of drugs, adding a little of each, which is very wrong, which not only can not control the seizure but also increases the interaction between drugs, easily leading to poisoning and drug resistance, and some even lead to drug-derived seizures. Abuse of Chinese medicine Abuse of Chinese medicine generally refers to taking pure Chinese medicine that is secretly adulterated with western medicine, which is the most abhorrent practice. The western drugs added to Chinese medicine are almost always inexpensive old anti-epileptic drugs, which are sold at an expensive price after being mixed with Chinese medicine, while the actual effect is often the western ingredients; most of the western drugs mixed are drugs with high side effects and obvious cognitive damage, and these anti-epileptic drugs are gradually being eliminated in recent years. These antiepileptic drugs are being phased out in recent years because the ingredients and dosage of the adulterated drugs are unknown, which can easily lead to poisoning or reduce the efficacy of other drugs due to drug interactions. The so-called pure Chinese medicine may be effective at the beginning, but after a long time, it often fails because of its own induction or drug inter-induction tolerance, and then switching to other drugs may also affect the efficacy. The best way to achieve the desired therapeutic effect is to arrange the medication schedule so that the peak blood concentration time covers the expected seizure period. The dose of medication should be larger in the evening than in the morning. The most important thing is to make sure that you have a good understanding of the situation. Otherwise, it will not only fail to control the seizure but also lead to cross-tolerance of the drug. The most common reason for this is that it is not necessary to stop the medication when the EEG is being reviewed. This often occurs due to the lack of comprehensive knowledge of epilepsy diagnosis and treatment among medical personnel. If patients who are under treatment and have their seizures fully controlled with medication are discontinued, the course of medication will have to be counted from the beginning. The patient should not only follow the doctor’s instructions during the treatment of epilepsy, but should also pay attention to avoiding the triggering factors of epilepsy, not taking the medication according to the doctor’s instructions and avoiding the triggering factors, reducing the medication, stopping the medication and changing the time of medication. Doctors should help patients find triggers and instruct them to avoid them; if necessary, check blood levels to check compliance. Gullible belief in treatments without scientific basis Gullible belief and acceptance of some treatments without any scientific basis, including buried wires, buried magnets, intracranial buried electrodes, etc., even Chinese medicine should not be fully believed, delaying the time of treatment. Some epileptic patients with intracranial lesions are not treated in time Some epileptic patients with poor drug treatment can be treated surgically, especially those with intracranial lesions, they should choose surgery. Patients with intracranial lesions, even though the seizures may be controlled for a short time, the long-term efficacy is definitely not good and they need to choose surgery or other methods of treatment in time. The above are common reasons for the failure of epilepsy treatment. These wrong practices often lead to poor disease treatment in epilepsy patients, which in turn leads to chronic refractory epilepsy, in fact, this part of the patients may have a very different effect if the diagnosis is determined and the individualized program is reasonably adjusted after treatment. In addition, some of the patients with poor treatment results should not lose confidence, not to mention the disease and believe in charlatan doctors. This group of patients with refractory epilepsy can be considered for epilepsy surgery under the guidance of a specialist.