Severe pancreatitis generally refers to severe acute pancreatitis, partially curable, it is recommended that patients need to take timely general measures to regulate, as well as drug therapy, surgical treatment. Patients with severe acute pancreatitis are more serious and not necessarily curable. It is recommended that patients with severe acute pancreatitis need to fast, and gastrointestinal decompression, and at the same time also need to take intravenous fluids and gastrointestinal nutrition therapy. In addition, patients can also use atropine, scopolamine and other antispasmodic analgesics, as well as octreotide and other growth-suppressor analogs under the guidance of the doctor. If patients with severe acute pancreatitis develop biliary tract infection or obstruction of the lower end of the common bile duct, as well as intestinal perforation, hemorrhage, and infection of the pancreas and peripancreatic necrotic tissues, surgical treatments such as necrotic tissue debridement with drainage are required. In addition, patients with biliary pancreatitis need to be treated with cholecystectomy. Whether or not a patient with severe acute pancreatitis can be cured, the patient needs to consult a doctor in time, and the doctor will determine the patient’s condition.