Pure ground glass nodule 5mm in the right lower lung, if it is benign, generally speaking, no treatment is needed, and follow-up observation is sufficient. If the nodule is malignant, further examination is needed to take appropriate treatment measures. Whether the right lower lung pure ground-glass nodule 5mm needs treatment or not, we need to improve the examination of tumor markers, and at the same time, combine with clinical symptoms, such as whether there is chest pain, cough, sputum, emaciation and other symptoms, to comprehensively determine whether the need for treatment. If there are signs of malignancy on imaging and elevated tumor markers, accompanied by clinical symptoms, thoracoscopic surgery is recommended, and histopathological examination is performed. In most cases, 5mm ground-glass lung nodules are benign, and can be left untreated for the time being for dynamic observation, with a repeat chest CT in 3-6 months to determine the changes in the nodule. If the nodule is significantly larger than before, further relevant examinations are needed, and treatment should be carried out according to the doctor’s instructions.