Clinically, it is common for patients with mild thrombocytopenia to come in for consultation or consultation. Patients and their families are often troubled and tormented by their clinical bleeding condition. In the hematology specialty, how do we view thrombocytopenia? How do we address the bleeding that people worry about as a result of thrombocytopenia? Here we introduce thrombocytopenia. The so-called thrombocytopenia is the routine blood test platelet count / count less than 100 * 109 / L, clinically, the degree of thrombocytopenia according to its number of different division methods, common can have the following division according to the risk of bleeding: 1, platelet count between 80-100 * 109 / L (mild thrombocytopenia), the risk of bleeding in such patients is not significantly different from the norm, can be surgery and other Invasive treatment; 2. Platelet count between 50-80*109/L (mild to moderate thrombocytopenia), the risk of bleeding in such patients is not significantly different from the norm and general surgical treatment can be performed, but major surgery such as cardiac and cranial surgery should still be appropriate to raise platelets to above 80*109/L; 3. Platelet count between 20-50*109/L (moderate thrombocytopenia), the The clinical situation is generally not obvious active bleeding (visible subcutaneous bleeding spots, etc.), but it is a relative contraindication to surgery and other invasive operations (that is, after the specialist consultation to weigh the advantages and disadvantages of the patient, and obtain the consent of the patient and family, with adequate preparation can be carried out urgently); 4, platelet count below 20 * 109/L (severe thrombocytopenia, especially platelet count in 10 * 109/L) 109/L for very severe thrombocytopenia), such patients have a higher risk of spontaneous bleeding, or even life-threatening bleeding such as intracranial bleeding, gastrointestinal bleeding, etc., and have indications for prophylactic platelet transfusion. In thrombocytopenia, we are most concerned about serious or even life-threatening bleeding, but as seen from the above analysis, the risk of spontaneous bleeding induced by thrombocytopenia generally occurs mainly in patients with severe or even very severe thrombocytopenia, and in general, patients with thrombocytopenia do not even notice any discomfort on their own, but only before physical examination or inpatient surgery. Therefore, patients with thrombocytopenia should mainly look for the cause of the disease, and treatment for the cause of the disease is the best policy, rather than focusing only on thrombocytopenia treatment, that is, symptomatic treatment. The common causes of thrombocytopenia are drug effects (e.g. antibiotics, anti-inflammatory and analgesic drugs, anti-tumor drugs, etc.), infections (various infections, including infectious diseases, chronic inflammatory stimuli), autoimmune diseases (e.g. systemic lupus erythematosus, etc.), thyroid diseases, tumors and related hematologic diseases. Therefore, patients with thrombocytopenia should take a detailed medical history and complete tests for indicators of rheumatologic and immunologic diseases, infectious diseases (febrile patients with special attention to the possibility of infection from local infectious diseases), thyroid diseases, neoplastic diseases and related hematologic diseases. Regarding the bleeding caused by acute thrombocytopenia, we should still identify the cause of its pathogenesis and provide emergency platelet transfusion (but at present, the domestic blood supply is very tight, and voluntary blood donation, especially platelet donation, is the source of blood, so we also call on everyone to actively donate blood), high-dose human immunoglobulin infusion or hormone treatment when necessary. （In summary, thrombocytopenia can be caused by a variety of diseases or even a “normal” state (sub-health), so the discovery of thrombocytopenia should be actively searched for the cause of the disease, and if necessary, go to a hematologist for consultation or consultation.