1. Many people want to know what is the incidence of Parkinson’s disease in China and what are the symptoms? How does having Parkinson’s disease affect the lives of older people? Parkinson’s disease is a kind of movement disorder disease that threatens the health of middle-aged and elderly people, and the incidence rate increases with age. According to a survey, among middle-aged and elderly people over 50 years old, there will be 5 Parkinson’s patients for every 10,000 people, and by the time they reach the age of 60 or above, the incidence rate of the disease can reach 1 in 1,000, according to which it is estimated that there are about 300 Parkinson’s disease patients with an incidence of Parkinson’s disease every year in Hainan Province. Medical research has found that Parkinson’s disease is a disease in which a series of motor dysfunctions are caused by reduced secretion or excessive consumption of the neurotransmitter dopamine in the brain. Its typical manifestations are muscle stiffness, slow movements and tremor (shaking). Patients with Parkinson’s disease may suffer from trembling of hands and feet, difficulty in self-care, or stiffness of the whole body, inability to turn over and get up, and in the late stage of development, it will also be complicated by visceral dysfunction, language and mental disorders, which not only affects the quality of their own lives, but also brings a heavy burden to their families. If Parkinson’s disease is not treated timely and correctly, it often leads to death in the late stage due to complications in various organs, the most common being pneumonia. At present, the public is still lack of sufficient understanding of Parkinson’s disease, that hand and foot tremors and stiffness of movement are normal phenomena when people get old, so not many Parkinson’s disease patients can get timely diagnosis and treatment. 2.What are the methods of treating Parkinson’s disease and what are the characteristics of each method? Nowadays, clinical control of Parkinson’s disease symptoms is mainly through drug treatment and surgical treatment. In the early stage of the onset of Parkinson’s disease, medication is preferred. As this is a degenerative disease of the central nervous system, with the prolongation of drug taking time, the efficacy of drug treatment decreases, in order to control the symptoms, patients need to increase the dosage of medication, and at the later stage, it often produces the “switch effect” (with the change of blood concentration in the movement and immobility of the sudden change between the switch); in addition, long-term medication will produce In addition, long-term use of drugs will produce toxic side effects, causing damage to the patient’s internal organs, and in the end, even if the poisoned dose of drugs can not control the symptoms. Surgery should be considered when the patient has difficulty with medication or when the side effects of medication are severe. Nowadays, the commonly used surgical treatments in the clinic are the application of stereotactic technology, which selects different nuclei in the brain for destruction or deep electrical stimulation according to the patient’s symptoms, and also the precise localization of the nuclei in the brain through cellular electrode recording. It should be said that both methods are effective in the treatment of Parkinson’s disease. However, deep electrical stimulation needs to bury electrodes in the brain, and the cost is expensive (about 100,000 yuan), so the stereotactic radiofrequency destruction method is still the “classic therapy” for Parkinson’s disease. Stereotactic nucleus destruction method is under the guidance of stereotactic instrument, the use of radiofrequency electrodes to destroy some special nerve nuclei in the brain, in order to reduce the depletion of dopamine transmitter, in order to improve the patient’s movement disorders (tremor, ankylosis, etc.), this method of treatment of Parkinson’s disease has a high efficiency, minimally invasive (under local anesthesia to complete), low cost (the cost of the operation is only a few thousand dollars), hospitalization time is short (can be discharged from the hospital within a week), quick recovery (after the operation can be discharged). Quick recovery (you can get out of bed after the surgery) and other advantages, is a “cost-effective” high treatment program. 3.Can you tell us about the surgical treatment of this disease in the neurosurgery department of the city hospital in relation to specific cases? This year, there is a case of Mr. Li, a 79-year-old man in Sanya City, who started to notice tremors in his right hand and foot since 2005. At first, he thought it was because of his age and didn’t pay attention to it, but as the tremors became more and more pronounced, he found it difficult to complete a daily action, and at the same time, his muscles became stiff and slow, and he had to hesitate and wait for a while before he could complete an action, which made his life seriously affected. His life was seriously affected, and that’s when he went to the local hospital for a checkup, and the doctor gave him the diagnosis of Parkinson’s disease! After three years of medication, Mr. Li found that the medication gradually lost its effect, and to make matters worse, his hands and feet on the left side also began to shake, and he needed the ministrations of his family in his daily life. Mr. Li’s condition is actually a typical Parkinson’s disease progression. With a strong desire for treatment, Mr. Li came from Sanya to the Neurosurgery Department of the hospital for help. Taking into account his specific situation, the doctors of the Neurosurgery Department decided to treat him with the surgical method of stereotactic nucleus pulposus destruction. Under the guidance of Prof. Shi Keshan, an expert with special allowance from the State Council, Lin Peng, Chen Weiming and other physicians and I made a complete surgical treatment plan for Mr. Li. Through MRI localization, under local anesthesia, we inserted an electrode needle into a special part of Mr. Xu’s brain, and electrically destroyed a mung-bean-sized lesion, and Mr. Li’s right side arms and legs stopped shaking right away, and his activities were flexible. Throughout the surgery, Mr. Li was able to converse easily with the doctor. The immediate results of the surgery made Mr. Li and his family praise the neurosurgery’s excellent technology. It is believed that with a better understanding of the clinical manifestations and treatments of Parkinson’s disease, more and more Parkinson’s patients will choose the right treatment to effectively improve their motor functions and better enjoy their old age.