If chemotherapy for carcinoma in situ is ineffective, other treatments can be chosen, such as surgery, radiotherapy and conservative treatment. 1. Surgery: Since carcinoma in situ is a cancer that involves the whole layer of cancer cells but has not broken through the basement membrane, surgery can be used to directly remove the diseased part, such as gastric cancer, esophageal cancer and so on. 2. Radiation therapy: mainly use rays to kill the diseased cancer cells, so as to reduce the size of the tumor, such as small cell lung cancer. 3. Conservative treatment: For some parts of carcinoma in situ, the development of the lesion is very slow, so it can be treated conservatively by strengthening nutrition, improving immunity through suitable exercise and improving immunity, etc., and some medicines can be used when necessary. For example, cervical cancer and basal cell carcinoma of the skin can be treated with conservative treatment. It is recommended to strictly follow the doctor’s prescription and actively cooperate with the treatment.