Patients with lupus erythematosus nephritis may experience fever and sweating, not necessarily hot flashes. Lupus nephritis is a disease of kidney damage due to systemic lupus erythematosus (SLE). Patients commonly present with prolonged and intermittent fever, proteinuria, edema, hypertension, and other SLE symptoms. As patients have prolonged fever, they may experience sweating and flushing of the cheeks, which is not necessarily hot flashes (a burst of fever). Lupus nephritis is prone to complications of chronic renal failure and anemia. Different types of lupus nephritis require different treatment plans, with drug therapy as the mainstay, aiming to protect patients’ renal function and prevent recurrence of the disease, and renal replacement therapy if necessary. It is recommended that patients with lupus nephritis who have fever go to the Department of Rheumatology and Immunology of regular hospitals in time to avoid delaying their condition.