I believe many parents have heard and understood about hives, and some have had similar personal experiences themselves! The sudden appearance of large, itchy bumps on the child’s body, which are obviously all over the body just now, but then disappear, often causes fear and concern among parents. Statistics show that about 1 in 4 people have had hives. The skin manifestations of hives come and go quickly. Itchy skin often appears first, followed by red bumps, which are bright red or pale, edematous red patches (i.e., “wind bumps”). The bumps last for a few minutes or hours (no more than 24 hours) and fade on their own, leaving no traces after fading. They can occur on all parts of the body and are often recurrent and recurring. Some may be accompanied by symptoms of gastrointestinal involvement such as nausea, vomiting, abdominal pain, diarrhea, etc. Some may also be accompanied by symptoms of bronchial and pharyngeal involvement such as chest tightness, discomfort, throat congestion or difficulty in breathing, and even systemic symptoms such as pallor, accelerated heart rate, weak pulse and decreased blood pressure. Urticaria caused by acute infection and other factors may be accompanied by high fever and increased white blood cells. Most urticaria improves within a short period of time and is called acute urticaria, but some children have recurrent urticaria for up to 6 weeks or more and are called chronic urticaria. The disease is easy to diagnose, but it is more difficult to determine the cause. The cause of most acute urticaria can be found, but the cause of chronic urticaria is very difficult to define. The etiology can be divided into exogenous and endogenous. Exogenous factors are mostly temporary and include food, food additives, drugs, physical stimuli, implants, and exercise; endogenous factors are mostly persistent and include infections, systemic diseases, inhalants, high sensitivity of mast cells to IgE, exertion, stress, mood swings, and endocrine changes, etc. Acute urticaria caused by infections is more common in children than adults. Most urticaria requires oral medication, so it is recommended that the first episode should not be treated on its own, but should be seen in a hospital for standardized treatment.