According to Chinese medicine, human diseases are caused by the imbalance of yin and yang in the internal organs and meridians, and the Yellow Emperor’s Classic of Internal Medicine says, “When yin and yang are secret, the spirit is cured; when yin and yang are separated from the decision, the essence is decided”, which means that the balance of yin and yang in human body is directly related to human health and life. Meridian voltammetric curve diagnosis system is a new type of meridian diagnosis system, using modern electrophysiological means to apply increasing detection voltage to specific points in the twelve meridians to obtain a series of current values, constituting volt-ampere characteristic curve data, forming a two-dimensional graph, the reliability, repeatability and information contained in the data obtained by this method is greater and more comprehensive than the information obtained by simple electrical impedance detection methods. The results will make up for the ambiguity and uncertainty of the internal organs and meridians in Chinese medicine, and help to objectively diagnose the changes of yin and yang of human organs and meridians. Mainly for three kinds of people: 1, subhealth state patients: such patients often have symptoms, examination and test but normal, can measure the corresponding meridian organs of the Yin and Yang deficiency cold and heat changes, so that doctors guide patients to diet life and self-massage adjustment, in order to achieve the purpose of non-pharmaceutical therapy to restore health. 2, difficult disease patients: If the patient’s diagnosis is unclear, or the diagnosis is clear with conventional treatment means but the effect is not good. Consider acupuncture or Chinese medicine treatment based on the results of meridian testing. 3, tumor patients: from the theory of Chinese medicine, the balance of yin and yang of the internal organs of tumor patients is continuously disrupted, and if the treatment can try to restore its balance, the patient’s life can be extended. With regular testing, this system can give acupuncture herbal guide a correct direction to maintain the balance of yin and yang.