Recently, we have performed three more cases of “partial embolization of splenic artery”, and after the postoperative follow-up, the patients’ clinical symptoms (vomiting blood and blood in stool) were significantly relieved, and the index of peripheral blood picture of three cell lines (white blood cells, red blood cells and platelets) was significantly increased, and the discomfort symptoms after embolization were less. Hypersplenism (splenomegaly), referred to as hypersplenism, is a syndrome, often caused by cirrhosis of the liver, etc.. The clinical manifestations include enlargement of the spleen, persistent reduction of one or more blood cells, portal hypertension, dilatation of the portal vein and esophagogastric fundic vein that can easily rupture and lead to vomiting and blood in the stool, and even life-threatening. The traditional treatment is surgical splenectomy. After removal of the spleen, the blood picture is restored, symptoms are relieved, portal pressure is reduced, and gastrointestinal bleeding is effectively avoided. Since it is usually a total splenectomy, it is more traumatic, has a longer recovery period, and loses the immune function of the spleen, so it is not easily accepted by some patients. Partial embolization of the splenic artery has been used for more than 20 years to treat hypersplenism, and it has a positive effect on reducing portal hypertension, correcting hypersplenism, preventing and treating ruptured esophagogastric vein bleeding, and restoring the blood picture. The disadvantage is that patients often experience varying degrees of abdominal pain and fever after surgery, which can be a deterrent for some patients. With the accumulation of clinical experience and improvement of technology (reasonable selection of embolic particles, appropriate application of postoperative hormones, reasonable application of heparin, etc.), postoperative discomfort is gradually disappearing, and more patients are slowly accepting this safe, effective, minimally invasive and fast recovery interventional treatment method. We also hope that this technology can benefit more patients.