In order for a woman to complete the normal process of conception, there must be a mature egg cell to be discharged, and the mature egg cell and sperm combine to form a fertilized egg, which is the first step to completing the process of fertility. Some women suffer from ovarian dysfunction that results in failure to ovulate or immature follicles, which can lead to infertility. Common causes include ovarian pathology, such as congenital ovarian insufficiency, polycystic ovary syndrome, premature ovarian failure, functional ovarian tumors, ovarian endometriosis cysts, etc.; disorders of the hypothalamus-pituitary-ovarian axis, resulting in anovulatory menstruation, amenorrhea, etc.; and systemic disorders (severe malnutrition, hyperthyroidism, etc.) affecting ovarian function, resulting in ovarian ovulation or follicular developmental abnormalities. Many diseases can lead to follicular development problems. The first step is to find the cause of the disease, treat the primary disease first, and then give treatment to promote follicular development. The side effects of the drugs used to promote ovulation are large, and due to the large individual differences, it is important to choose the right drugs and treatment plan under the guidance of a medical professional. The causes of follicular immaturity in women are complex, and should be treated in a timely manner for different causes.