A high CA125 test during menstruation may be normal. However, pelvic inflammatory disease, ovarian cancer, endometrial cancer, etc. can also lead to elevated CA125. Therefore, it needs to be combined with other examination results and physical signs to make a comprehensive judgment and actively treat the disease after clarifying the cause. Common causes and treatment I. Normal physiological conditions: CA125 can be mildly elevated during menstruation and in early pregnancy, which are normal physiological conditions. The typical symptoms are persistent lower abdominal pain, fever, prolonged menstruation, etc. The treatment drugs can be cephalosporins and penicillins, and in severe cases, two kinds of antibiotics can be combined. CA125 is an important marker for ovarian cancer detection, especially for plasma ovarian cancer. In addition to elevated CA125, patients with ovarian cancer may have menstrual disorders and amenorrhea, and gynecological examination may detect adnexal masses. Surgery is usually required, and chemotherapy is administered to patients who do not tolerate surgery; 3. Endometrial cancer: CA125 can also be elevated in endometrial cancer, which is usually characterized by irregular vaginal bleeding, accompanied by increased vaginal discharge and paroxysmal lower abdominal pain. Diagnosis is more sensitive but less specific, because many tumor diseases such as breast cancer, pancreatic cancer, gastric cancer, lung cancer, etc. can have increased CA125. Precautions After CA125 is found to be elevated during menstruation, it can be retested after the menstrual period has passed. While waiting for the review, you should pay attention to the improvement of diet and living habits, avoid spicy, stimulating and cold foods, reduce staying up late, adjust your psychological state and maintain a healthy attitude towards life.