The size of the gland thickness suggested by ultrasound, just like the difference in breast size, has no real significance. Ultrasound suggestive of hypoechogenic nodules of a certain size is usually suggestive of hyperplastic nodules, if it is anechoic it is usually a cyst, in a few cases hypoechogenicity along with other ultrasound manifestations such as presence of blood flow etc. may suggest a tumor, both benign and malignant, and the ultrasonographer will usually give the appropriate conclusion. Therefore, just look at the ultrasound findings. If it is a typical tumor, the sonographer will point out in the findings such as fibroadenoma is more likely or parenchymal occupancy is more likely. If it is just hypoechoic, or non-echoic, it is usually just a hyperplastic nodule or cyst. Also, ultrasound can only give hints to help the doctor make a diagnosis. It is not the final diagnosis. The final diagnosis can only rely on pathology. Blood flow signal, which may indicate a tumor, but scarring, severe, menstruation, etc. can also be seen; just an indicator. About mammary hyperplasia nodules and cystic changes: The breast is an endocrine target organ, and the glands of the breast are affected by changes in the level of endocrine hormones in the body throughout their life, mammary hyperplasia nodules and cystic changes are degenerative changes in the gland under the influence of the endocrine environment. Malignant changes definitely occur on the basis of hyperplasia, but the pathogenic mechanism is very complex, and there are many pathogenic factors, and no one in the world can perfectly explain the exact mechanism of malignant changes yet. Doctors cannot accurately predict which hyperplasia will definitely become malignant, but can only tell what kind of hyperplasia needs to be alerted and needs to be closely followed and observed; therefore, it is impossible to prevent tumors by trying to cure hyperplasia. The key point is that the malignant rate of hyperplasia is only a few parts per thousand or even a few parts per ten thousand in the general population, so there is no need to worry about hyperplastic nodules and cystic changes. Surgical treatment is only necessary if malignancy is suspected to exist. Hyperplasia and cystic changes (cysts) and breast pain are not addressed by surgery. In addition, sometimes ultrasound alone is not enough to determine if malignancy is present, and an experienced specialist is needed to make a comprehensive determination by combining physical examination, ultrasound and mammogram. It is also important to remind readers that specialists, ultrasound doctors and mammography doctors have different levels of experience; therefore, the value of the ultrasound report is based on its source and which hospital and which doctor are responsible for the diagnosis.