In daily life, when faced with sudden and severe pain in the lower back and abdomen accompanied by nausea and vomiting, how should we respond? First of all, although the pain is very severe, sometimes even unable to stand, patients and family members should remain calm. You can simply check the location of the pain, is it on the left or right side, or both sides at the same time? Is there any hematuria? What is the color of the face? Is there vomiting? What did you vomit? For patients who have no history of stones or who have not had similar pain episodes in the past, it is more important to remember the location of the pain, the duration of the pain, and the symptoms that accompany the pain so that the doctor can rule out some acute abdominal conditions that need urgent attention as soon as possible. Second, go immediately to the nearest or familiar hospital. Do not eat any food, including water, after the onset of pain and before the hospital visit. You can reduce the patient’s pain by changing the position, keeping warm, and comforting the patient emotionally before arriving at the hospital. Try not to urinate before arriving at the hospital because doctors often need to determine whether it is renal colic through urine tests. After the doctor’s diagnosis is clear, drugs such as dulcolax, progesterone and atropine can be used to relieve spasm and pain, and hydrate. Usually renal colic will get better immediately after medication, and hospitalization is not necessary. Finally, relevant ultrasonography or imaging is performed to clarify the stone condition and prepare for further treatment left. If the stone is less than 1cm and there is no obvious hydronephrosis, you can promote the stone discharge by exercising more, taking lithotripsy medication and drinking more water. It is better to filter urine with gauze when urinating during stone removal to observe whether the stones are expelled. For larger stones, or patients with smaller stones but significant hydronephrosis, early surgical intervention is needed.