Impotence patients can use to the treatment of drugs mainly include type 5 phosphodiesterase inhibitors and testosterone undecanoate, etc., while patients with premature ejaculation can use the treatment of drugs mainly 5-hydroxytryptamine reuptake inhibitors and local anesthetics and so on. 1. impotence: (1) Type 5 phosphodiesterase inhibitors: clinically used in the treatment of impotence, type 5 phosphodiesterase inhibitor drugs, mainly sildenafil, tadalafil, vardenafil, etc., the use of on-demand treatment and regular treatment. Common adverse reactions caused by these drugs include headache, facial flushing, dyspepsia, nasal congestion, and dizziness. (2) Testosterone undecanoate: endocrine impotence can be used to the androgen replacement therapy, so impotence suffering from hypogonadotropic hypogonadism, in the case of low testosterone levels, can be used to testosterone undecanoate for treatment, but suffering from prostate cancer or prostate cancer metastasis is a contraindication population. 2. Premature ejaculation: (1) 5-hydroxytryptamine reuptake inhibitors are the main therapeutic drugs for the treatment of premature ejaculation, including dapoxetine and so on. However, the use of such drugs may cause headache, nausea, dizziness, diarrhea and other adverse reactions. (2) Local anesthetics: local anesthetics are used to treat premature ejaculation by delaying the ejaculation latency time by decreasing the sensitivity of the penis head, such as compound lidocaine cream, Dacronin and so on. Men, whether suffering from impotence or premature ejaculation, should not use their own medication, and any medication must be applied under the guidance of a professional physician. Individuals who experience sexual dysfunction should seek medical attention.