Chronic urticaria is an allergic disease of the skin and mucous membranes, characterized by symptoms such as transient, limited, edematous with severe itching and recurrent attacks lasting more than 1.5 months. 1. Etiology The causes of chronic urticaria are complex, and the common causes can be summarized as follows. 1.1.1 Food: eating certain foods, especially protein-rich items, such as fish (cod), shrimp, crab, milk, walnuts, etc. 1.1.2 Drugs: penicillins, sulfonamides, antipyretics and analgesics, vaccines, vitamin B, etc. 1.1.3 Infections: parasitic infections (Ascaris lumbricoides, schistosomes, Plasmodium), viral infections (hepatitis, infectious mononucleosis), bacterial infections (alveolar abscess, tonsillitis, suppurative mastitis, Helicobacter pylori gastropathy), fungal infections (Candida albicans, ringworm disease), etc. 1.1.4 Inhalant dust: (powder) mites have the highest positive rate, followed by: house dust, fungal spores, animal dander, feathers, volatile chemicals, other airborne allergens. 1.1.5 Endocrine and other system diseases: hyperthyroidism, diabetes mellitus, leukemia, lymphoma. 1.1.6 Mental factors: mood swings, mental stress, depression, etc. can trigger the disease. 1.1.7 Physical and chemical factors: cold, heat, sunlight, friction and pressure, mechanical stimulation, certain chemical substances into the body and the onset of the disease. 1.1.8 Other factors: people with certain disorders of gastric motor function. Immune dysfunction and genetic factors. 2. Treatment 2.1 If the cause is clear (or possible), treatment of the cause can be carried out to eliminate the inhalation, contact, ingestion and use of harmful factors; if it is caused by drugs, the drug should be banned and similar drugs should be used with caution; if it is caused by bacterial, fungal or parasitic infections, antibacterial, antifungal and anthelmintic treatment should be carried out; if it is caused by reduced gastric motility, gastric motility drugs should be used to promote gastric motility. For those allergens that cannot be avoided, specific desensitization therapy is the only causal treatment. 2.2 For causes that are difficult to detect, symptomatic treatment is often used. 2.2.1 Antihistamine drug therapy: (1) H1 receptor antagonists: cyproheptadine tablets, isoproterenol tablets, anterol tablets, methaqualazine tablets, cerebral promethazine tablets, loratadine tablets, squizostine tablets, azelastine tablets, clomastine tablets, seltzer tablets, epastine tablets, etc.; (2) H2 receptor antagonists: cimetidine tablets, ranitidine capsules, famotidine tablets. The above antihistamines H1, H2 receptor antagonists, often combined with the treatment effect is better, treatment should be more than 20d, for the recalcitrant can be extended appropriately, and use the decreasing method. 2.2.2 Calcium agents: calcium gluconate, calcium chloride, sodium bromide. 2.2.3 Non-antihistamines: hemostatic aromatic acid injection, anorectic acid tablet, nifedipine tablet, magnesium sulfate injection, peptidase injection, pansentin tablet, lisinopril tablet, sodium thiosulfate injection, procaine injection, tretinoin tablet, doxycycline injection. 2.2.4 Immunomodulators: Skikon needle, transfer factor needle, kallikrein needle, thin ganoderma tablets, thymidine needle, histamine globulin needle, interleukin needle. 2.2.5 Acupuncture point therapy. 2.2.6 Autologous blood therapy. 2.2.7 Herbal soup daily.