If you have difficulty breathing and can’t get air during sleep, consider the possibility of cardiopulmonary disease, as follows: 1. Acute bronchial asthma attacks: Young people are more common because bronchial asthma attacks are often at night, and vagal nerve excitation at night leads to bronchoconstriction and spasm, resulting in difficulty breathing and can’t get air. 2. Chronic obstructive pulmonary disease and cardiac insufficiency. The elderly are often seen in chronic obstructive pulmonary disease and various causes of cardiac insufficiency, which can be clarified by timely improvement of pulmonary function, chest X-ray or lung CT examination. 3, sleep apnea hypoventilation syndrome: this can occur suddenly during sleep, dyspnea and inability to get air, caused by the presence of hypoxia at night, which can be clarified by improving polysomnography monitoring.