At this point, I usually close the door and ask the patient carefully. The patient’s voice is usually very low, with a sense of guilt, self-blame, fear of getting STD AIDS, and will ask some strange questions, “Do you see this lump on your body is AIDS? Is there any relationship between diarrhea and AIDS? Is this a hairy tongue? Is the small pimple on my glans a wart? Is this small blister genital herpes? This kind of people usually have seen a lot of hospitals, and then a lot of information on the Internet, each doctor will usually see two or three times. The actual fact is that you can find a lot of people who are not in a position to get a lot of money, but you can get a lot of people who are not in a position to get a lot of money. In fact, in clinical practice, patients with STD phobia often have both STD hypochondriasis and STD obsessive-compulsive disorder. In the former case, patients are overly concerned about their genital health and suspect that they are suffering from STDs, but this suspicion does not correspond to the actual situation. The above conditions can exist independently or can be combined or crossed over. Most of these patients can present with tension, anxiety, paranoia, depression, terror, insomnia, poor appetite, compulsion, abnormal sexual function, multiple somatic discomfort, etc. In the clinical work of STD prevention and control, the general diagnosis is STD phobia, and no separate STD hypochondriasis or STD obsessive-compulsive disorder is established. In the clinical work of STD throughout China, patients with STD phobia can be encountered, but there is no systematic report about it yet. According to scattered reports, there are more males than females, with the greatest number of patients aged 20 to 45 years old. Most patients have a history of extramarital sexual contact or have had an STD, and the majority lack knowledge of STDs. Highly afraid and worried that they are suffering from STD, although the physical examination and laboratory tests have indeed indicated that they are cured or have never had STD, the patients still firmly believe in their own opinions, suspect that the doctors’ medical skills, poor laboratory equipment, improper technical operation and wrong test results, and keep changing doctors and hospitals for consultation. The patient complains of scattered and diverse symptoms, associates discomfort in other areas with STDs, has the ability to observe extremely subtle changes in the genital area in great detail, and considers otherwise normal manifestations as manifestations of lesions. Patients are very detailed in their medical history and provide the doctor with evidence of what they believe to be an STD. They believe that their condition is serious and are worried, and some suspect that their spouse or children have also contracted an STD and are therefore repentant and guilty. Most patients may experience nervousness, panic or anxiety, complain of urethral “discharge”, discomfort, burning sensation, lower limbs or perineum swelling and discomfort, symptoms such as loss of libido, impotence, seminal emission, premature ejaculation, irregular menstruation and back pain, as well as dizziness, fatigue, palpitations, poor appetite, dreaminess, insomnia However, no positive signs are found in genitourinary system and general examination. The doctor should listen patiently to the patient, study the medical history and do a careful examination. After fully understanding the situation and gaining the patient’s trust and cooperation, he/she should explain and persuade, or even reassure, the patient in scientific and popular language. If necessary, repeat the relevant clinical and laboratory tests again to dispel the patient’s doubts. Encourage the patient to make reasonable arrangements for work and life, and participate in cultural and sports activities appropriately to divert the patient’s attention. Seek the care and support of family members as much as possible. When patients have symptoms of panic, anxiety and restlessness, they can use anti-anxiety drugs, such as Valium, Xanax, Librium and Antalac, and if they are depressed, they can use drugs such as Amitriptyline and Doxepin. For some systemic discomfort, symptomatic treatment is available. The best way to avoid STD phobia is to go to the hospital to professional doctors for examination, combined with blood tests can be very good to rule out STDs, while avoiding the Internet to retrieve such diseases, but also to learn more about the differential diagnosis of some STDs, such as immune diseases and drug allergies may have similar symptoms. If you still can’t get rid of the fear you can find a psychiatrist for psychological counseling. If you are not infected with a sexually transmitted disease after a high-risk behavior is diagnosed by a professional doctor, you should not fall into the fear of sexually transmitted diseases, and take this as a wake-up call to consider it as a gift from God to yourself and cherish life more, instead it can be a valuable lesson in life.