Radiotherapy for breast cancer is a local treatment process, which generally does not affect the whole body and the chance of whole body pain is low. There are the following reasons for the whole body pain after radiotherapy for breast cancer: 1, osteoporosis of the whole body, first of all, breast cancer has the characteristics of female disease, during the treatment process, due to the effect of chemotherapy drugs and endocrine drugs, it can cause a large amount of calcium loss in the body, resulting in osteoporosis and whole body bone pain. It is recommended that patients should get more sunlight, pay attention to food calcium supplementation, and regular medication calcium supplementation if necessary. 2. For the progression of the disease and the phenomenon of bone metastasis throughout the body, patients need to consult a doctor in time and have a comprehensive examination to clarify the disease as early as possible, treat it as early as possible and relieve the pain.