White blood cells are a group of blood cells that have a defensive and protective effect on the body and are produced in the bone marrow. If white blood cells are reduced, the body is susceptible to various infections. If you have a blood count below the low end of normal during a physical examination or medical consultation, you may be diagnosed with leukopenia. In this case, it is important to pay attention to the cause of leukopenia and to seek medical attention for active treatment. There are many causes of leukopenia, and certain drugs can affect the number and function of leukocytes, so which drugs are likely to cause leukopenia? The following are collected for your reference and backup.
Anticancer drugs.
Alkylating agents, antimetabolites, anthracyclines, vincristine, such as methotrexate, cyclophosphamide, nitrogen mustard, 5-fluorouracil, vincristine, adriamycin, cytarabine, cisplatin, hydroxyurea and other chemotherapy drugs.
Drugs that occasionally cause granulocytopenia.
Antipyretics and analgesics.
Anacin, aminopyrine, pautazone, acetaminophen, aspirin, indomethacin, etc.
Sedative drugs.
Chlorpromazine, clozapine, barbiturates.
Antibacterial drugs.
Chloramphenicol, streptomycin, rifampin, isoniazid, penicillins, cephalosporins, vancomycin, quinolones, sulfonamides.
Anti-thyroid drugs.
Methimazole, methimazole, propylthiouracil, tapazole, hyperthyroidism, etc.
Anticonvulsants, antiepileptics and antipsychotics.
Phenytoin sodium, mephentermine, carbamazepine, trimethoprim, clozapine, chlorpromazine, etc.
Anti-arrhythmic drugs.
Procainamide, propranolol, quinidine.
Glucose-lowering drugs.
Glibenclamide, gliclazide, gliquidone, etc.
Diuretics.
Acetazolamide, etc.
Anti-hypertensives.
Methyldopa, captopril, etc.
Antihistamines.
Cimetidine, trimethoprim, etc.
Antimalarials.
Quinine
Others.
Interferon, allopurinol, levamisole, cyanase amine, gold salts, mercury preparations, etc.
In conclusion, long-term use of the above-mentioned drugs should be reviewed regularly for routine blood tests, and if leukopenia is detected, it should be used with caution or discontinued, and diagnostic treatment should be carried out under the guidance of a specialist.