The normal value of human red blood cells is (4.0-5.5) × 1012/L for adult males and (3.5-5.0) × 1012/L for adult females. When the red blood cell count is consistently higher than this normal value, it is called erythrocytosis.
The normal value of hemoglobin is 120-160 g/L for adult males and 110-150 g/L for adult females. When the hemoglobin concentration is consistently higher than this normal value, it is called hemoglobinopoiesis.
There are many reasons for high erythrocyte hemoglobin concentration, mainly including the following two aspects: 1. Relative increase in erythrocytes: Mostly due to the loss of water in the body, blood concentration resulting in a relative increase in erythrocytes, seen in severe vomiting and diarrhea, massive sweating, large burns, diabetic ketoacidosis, etc.
2, absolute increase in erythrocytes: that is, the clinical term erythrocytosis, including two, one is secondary erythrocytosis, seen in cyanotic precocious heart disease, obstructive emphysema, pulmonary heart disease, newborns or those living in the plateau, as well as hepatocellular carcinoma, ovarian cancer fibroids or hydronephrosis. Another type of primary erythropoiesis is seen in clonal hematopoietic stem cell disorders, also known as true erythropoietic disorders, and erythropoietic disorders caused by mutations in the erythropoietin (EPO) receptor.
Severe erythropoiesis can increase the viscosity of the blood in the body and lead to uncomfortable symptoms such as headache, dizziness, fatigue, etc. Seriously to the occurrence of cerebral infarction and other embolic manifestations, should be promptly consulted to receive a comprehensive diagnosis.
To sum up, the causes of high red blood cell hemoglobin concentration in the body are mainly the above two aspects, but the specific causes need to be combined with the patient’s medical history and other relevant laboratory tests to confirm the diagnosis.