The incubation period of hand, foot and mouth disease is 3 to 5 days, with low-grade fever, general malaise, abdominal pain and other antecedents. 1 to 2 days, the oral cavity, pharynx, soft palate, buccal mucosa, tongue, gums, painful corn to mung-bean sized blisters, surrounded by a red halo, broken into small ulcers, due to the pain, salivation and refusal to eat. Causes of painful corn to blisters on the tongue and gums There are several viruses that can cause HFMD. The most common is coxsackievirus A16, but also other strains of coxsackievirus A or enterovirus 71 can cause HFMD. Coxsackievirus is a type of enterovirus. Enteroviruses include poliovirus, coxsackievirus and echovirus. Their site of infection is the entire digestive tract, including the mouth. They enter the body through the mouth via contaminated food, drinks, and fruits, and proliferate in the intestines. HFMD occurs mainly in children under 4 years of age, but adults can also get it, so it can be said that everyone is susceptible. After infection, only the immunity of that type of virus is acquired, and there is no cross immunity to reinfection with other types of viruses, i.e., after having HFMD, it is possible to be infected with other types of viruses and get HFMD again.